SCHEMBL154048

SCHEMBL154048

CC(=O)[C@]1(O)C=C[C@H]2[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3C)[C@H]1O5

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MRGPRX2 Q96LB1 4/20 1.00
OPRM1 P35372 9/20 0.62
OPRD1 P41143 9/20 0.61
OPRK1 P41145 7/20 0.61
SLC22A1 O15245 1/20 0.61
ADRA2A P08913 1/20 0.61
ARRB1 P49407 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29583693 1.00 MRGPRX2 (1.00) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
SCHEMBL29449917 1.00 MRGPRX2 (1.00) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
Hydrochloric Acid SCHEMBL27754570 0.99 MRGPRX2 (0.98) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
Methoxymethane SCHEMBL27466715 0.97 MRGPRX2 (0.94) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
SCHEMBL10527174 0.90 MRGPRX2 (0.82) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
SCHEMBL8362208 0.90 MRGPRX2 (0.81) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
SCHEMBL8356924 0.88 MRGPRX2 (0.79) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
SCHEMBL5108263 0.88 MRGPRX2 (1.00) MRGPRX2OPRM1OPRD1OPRK1
SCHEMBL29459625 0.88 MRGPRX2 (1.00) MRGPRX2OPRM1OPRD1OPRK1
Hydrochloric Acid SCHEMBL8168636 0.87 MRGPRX2 (0.98) MRGPRX2OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1091 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12523669-B2 Methods and systems for improved quality assurance for high-throughput analysis LABORATORY CORPORATION OF AMERICA HOLDINGS (US) 2026-01-13 US claimed
US-20250304722-A1 ANTI-NALOXONE AND ANTI-NALTREXONE MONOCLONAL ANTIBODIES AND METHODS OF PRODUCTION AND USE THEREOF SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2025-10-02 US claimed
US-12429484-B2 Homogeneous enzyme immunoassay for keratinized structures PSYCHEMEDICS CORPORATION (US) 2025-09-30 US claimed
US-12385919-B2 2025-08-12 US claimed
US-12364430-B2 Wearable device for continuous monitoring of user health for accurate clinical outcomes and wellness programs KURANI HETAL B (US) 2025-07-22 US claimed
CN-117654455-B Purifying and extracting composition, kit and method for determining drugs and fentanyl drugs in biological sample 宁波市疾病预防控制中心(宁波市健康教育与促进中心) 2025-06-10 CN claimed
WO-2025111546-A1 DEVELOPMENT OF BROAD-SPECTRUM ANTI-OPIOID VACCINES BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2025-05-30 WO claimed
US-20250157623-A1 WEARABLE DEVICE FOR CONTINUOUS MONITORING OF USER HEALTH FOR ACCURATE CLINICAL OUTCOMES AND WELLNESS PROGRAMS KURANI HEMAL B (US) 2025-05-15 US claimed
US-20250130211-A1 METHOD OF SCREENING NEW PSYCHOACTIVE SUBSTANCE AND PLATFORM THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2025-04-24 US claimed
EP-3983127-B1 PLASMA SEPARATION AND SAMPLE METERING DEVICE AND METHODS OF USE RELATED THERETO SIEMENS HEALTHCARE DIAGNOSTICS INC (US) 2025-04-23 EP claimed
EP-0649465-B1 MORPHINONE REDUCTASE FOR THE PREPARATION OF HYDROMORPHONE AND HYDROCODONE MACFARLAN SMITH LTD (GB) 2002-07-24 EP claimed
EP-1027609-A2 METHOD FOR DETERMINATION OF DRUGS OF ABUSE IN BIOLOGICAL SAMPLES Varian, Inc. (US) 2000-08-16 EP claimed
WO-1999022244-B1 METHOD FOR DETERMINATION OF DRUGS OF ABUSE IN BIOLOGICAL SAMPLES VARIAN INC (US) 1999-09-10 WO claimed
WO-1999022244-A2 METHOD FOR DETERMINATION OF DRUGS OF ABUSE IN BIOLOGICAL SAMPLES VARIAN, INC. (US) 1999-05-06 WO claimed
US-5571685-A POLYPEPTIDES IN SYNTHESIS OF ANALGESICS MACFARLAN SMITH LIMITED (GB) 1996-11-05 US claimed
EP-0471740-B1 ENZYMES AND THEIR USE IN DRUG DETECTION BRITISH TECH GROUP (GB) 1995-08-09 EP claimed
US-5387515-A Oxidation in the presence of the enzyme and cofactor nadp BRITISH TECHNOLOGY GROUP LIMITED (GB) 1995-02-07 US claimed
US-5298414-A Polypeptides, oxidation for detection BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-03-29 US claimed
EP-0471740-A1 ENZYMES AND THEIR USE IN DRUG DETECTION. NAT RES DEV (GB) 1992-02-26 EP claimed
WO-1990013634-A2 ENZYMES AND THEIR USE IN DRUG DETECTION NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1990-11-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304722-A1 ANTI-NALOXONE AND ANTI-NALTREXONE MONOCLONAL ANTIBODIES AND METHODS OF PRODUCTION AND USE THEREOF OPRK1, OPRM1, OPRL1 MRGPRX2 1670/4885OPRM1 2/4885OPRD1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.