SCHEMBL29449917

SCHEMBL29449917

CC(=O)[C@]1(O)C=C[C@H]2[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3C)[C@H]1O5

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MRGPRX2 Q96LB1 4/20 1.00
OPRM1 P35372 9/20 0.62
OPRD1 P41143 9/20 0.61
OPRK1 P41145 7/20 0.61
SLC22A1 O15245 1/20 0.61
ADRA2A P08913 1/20 0.61
ARRB1 P49407 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29583693 1.00 MRGPRX2 (1.00) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
SCHEMBL154048 1.00 MRGPRX2 (1.00) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
Hydrochloric Acid SCHEMBL27754570 0.99 MRGPRX2 (0.98) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
Methoxymethane SCHEMBL27466715 0.97 MRGPRX2 (0.94) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
SCHEMBL10527174 0.90 MRGPRX2 (0.82) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
SCHEMBL8362208 0.90 MRGPRX2 (0.81) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
SCHEMBL8356924 0.88 MRGPRX2 (0.79) MRGPRX2OPRM1OPRD1OPRK1SLC22A1
SCHEMBL5108263 0.88 MRGPRX2 (1.00) MRGPRX2OPRM1OPRD1OPRK1
SCHEMBL29459625 0.88 MRGPRX2 (1.00) MRGPRX2OPRM1OPRD1OPRK1
Hydrochloric Acid SCHEMBL8168636 0.87 MRGPRX2 (0.98) MRGPRX2OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119178875-A Detection O6Test strip of monoacetylmorphine and methamphetamine and detection method 重庆医科大学 2024-12-24 CN claimed
CN-119125344-A Method for determining drugs in sewage by ultra-high performance liquid chromatography-tandem mass spectrometry and application thereof 江苏省理化测试中心(江苏省理化测试技术研究所) 2024-12-13 CN claimed
CN-115290803-A LC-MS/MS qualitative and quantitative analysis method for 9 drugs in hair 广州金域司法鉴定技术有限公司 2022-11-04 CN claimed
EP-4014051-A1 HOMOGENEOUS ENZYME IMMUNOASSAY FOR KERATINIZED STRUCTURES Psychemedics Corporation (US) 2022-06-22 EP claimed
EP-3983127-A1 PLASMA SEPARATION AND SAMPLE METERING DEVICE AND KITS AND METHODS OF USE RELATED THERETO Siemens Healthcare Diagnostics, Inc. (US) 2022-04-20 EP claimed
CN-122031596-A Application of compound preparation with effects of clearing away heart fire and soothing nerves in preparation of insomnia improving product 中国中医科学院医学实验中心 2026-05-15 CN disclosed
US-12594330-B2 Anti-opioid compounds and methods of making and using same REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2026-04-07 US disclosed
EP-4713957-A1 DOUBLE SINGLE-ION MONITORING MASS SPECTROMETRY Roche Diagnostics GmbH (DE) 2026-03-25 EP disclosed
US-12523669-B2 Methods and systems for improved quality assurance for high-throughput analysis LABORATORY CORPORATION OF AMERICA HOLDINGS (US) 2026-01-13 US disclosed
EP-4627350-A1 DETECTION OF AN ANALYTE OF INTEREST BY A CHIP BASED NANOESI DETECTION SYSTEM F. Hoffmann-La Roche AG (CH) 2025-10-08 EP disclosed
US-12429484-B2 Homogeneous enzyme immunoassay for keratinized structures PSYCHEMEDICS CORPORATION (US) 2025-09-30 US disclosed
US-12385919-B2 2025-08-12 US disclosed
US-20220296707-A1 ANTI-OPIOID COMPOUNDS AND METHODS OF MAKING AND USING SAME REGENTS OF THE UNIVERSITY OF MINNESOTA 2022-09-22 US disclosed
EP-4045035-A1 TLR7/8 AGONISTS TO ENHANCE IMMUNE RESPONSES IN OPIOID USING INDIVIDUALS Children's Medical Center Corporation (US) 2022-08-24 EP disclosed
EP-4014051-A1 HOMOGENEOUS ENZYME IMMUNOASSAY FOR KERATINIZED STRUCTURES Psychemedics Corporation (US) 2022-06-22 EP disclosed
US-20220120748-A1 HOMOGENEOUS ENZYME IMMUNOASSAY FOR KERATINIZED STRUCTURES PSYCHEMEDICS CORPORATION 2022-04-21 US disclosed
EP-3983127-A1 PLASMA SEPARATION AND SAMPLE METERING DEVICE AND KITS AND METHODS OF USE RELATED THERETO Siemens Healthcare Diagnostics, Inc. (US) 2022-04-20 EP disclosed
WO-2022073099-A1 METALIZED NANO COATED SWAB FOR TRACE DETECTION GREEN BELTING INDUSTRIES LTD. (CA) 2022-04-14 WO disclosed
US-20220080042-A1 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE ALERE SAN DIEGO, INC. 2022-03-17 US disclosed
US-20220080042-A1 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE ALERE SAN DIEGO, INC. 2022-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220080042-A1 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE DNPEP, CRHBP, AANAT MRGPRX2 347/4885OPRM1 11/4885OPRD1 30/4885
US-12594330-B2 Anti-opioid compounds and methods of making and using same OPRD1, OPRK1, OPRL1 MRGPRX2 854/4885OPRM1 4/4885OPRD1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.