Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1048787 | 0.78 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2ANPEPENPEPL3MBTL1 | |
| SCHEMBL321619 | 0.77 | PIK3CD (0.50) | LMNASMN1; SMN2L3MBTL1S1PR5HSD17B10 | |
| SCHEMBL28098432 | 0.75 | L3MBTL1 (0.40) | LMNASMN1; SMN2L3MBTL1S1PR5KDM4E | |
| SCHEMBL11308867 | 0.74 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2L3MBTL1S1PR5HSD17B10 | |
| SCHEMBL12465587 | 0.74 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2L3MBTL1S1PR5S1PR4 | |
| SCHEMBL19113012 | 0.74 | GNAO1 (0.32) | — | |
| SCHEMBL13905848 | 0.73 | LMNA (0.49) | LMNASMN1; SMN2L3MBTL1S1PR5PLG | |
| SCHEMBL6975583 | 0.72 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2L3MBTL1S1PR5S1PR4 | |
| SCHEMBL4115964 | 0.72 | MEN1 (0.41) | LMNAANPEPL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL13821435 | 0.72 | MEN1 (0.41) | LMNAANPEPL3MBTL1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448926-A1 | FLAVIN DERIVATIVES | Biorelix, Inc. (US) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011008247-A1 | FLAVIN DERIVATIVES | BIORELIX, INC. (US) | 2011-01-20 | — | — | WO | disclosed |