Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 8/20 | 0.71 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.71 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.61 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.61 |
| ▸ | CTSV | O60911 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9094091 | 0.85 | AKR1C3 (0.82) | AKR1C3AKR1C2MAPTHPGDMEN1 | |
| SCHEMBL10531801 | 0.84 | MAPT (0.56) | AKR1C3AKR1C2MAPTHPGDMEN1 | |
| SCHEMBL9622892 | 0.84 | MAPT (0.56) | AKR1C3AKR1C2MAPTHPGDMEN1 | |
| SCHEMBL10531772 | 0.81 | L3MBTL1 (0.52) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL22720146 | 0.81 | CTSV (0.81) | AKR1C3AKR1C2MAPTHPGDMEN1 | |
| SCHEMBL23567 | 0.81 | AKR1C3 (0.67) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL29785279 | 0.81 | AKR1C3 (0.67) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL29377063 | 0.81 | AKR1C3 (0.67) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL109591 | 0.81 | MAPT (0.53) | AKR1C3AKR1C2MAPTHPGDMEN1 | |
| SCHEMBL22720113 | 0.80 | MEN1 (0.72) | AKR1C3AKR1C2MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4859206-A | Hair dye preparations containing nitrodiphenylamine derivative | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-08-22 | — | — | US | claimed |
| US-4859206-A | Hair dye preparations containing nitrodiphenylamine derivative | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-08-22 | — | — | US | disclosed |