Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.45 |
| ▸ | WNT3A | P56704 | 2/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL5070094 | 0.92 | KDM4E (0.51) | KDM4ESMN1; SMN2RAB9AALDH1A1HPGD | |
| Benzimidazole SCHEMBL4371075 | 0.92 | KDM4E (0.51) | KDM4ESMN1; SMN2RAB9AALDH1A1HPGD | |
| Benzimidazole SCHEMBL158526 | 0.91 | SMN1; SMN2 (0.54) | KDM4ESMN1; SMN2RAB9AALDH1A1HPGD | |
| Benzimidazole SCHEMBL9028632 | 0.89 | SMN1; SMN2 (0.49) | KDM4ESMN1; SMN2RAB9AALDH1A1HPGD | |
| Benzimidazole SCHEMBL16516335 | 0.86 | SMN1; SMN2 (0.57) | KDM4ESMN1; SMN2RAB9AALDH1A1HPGD | |
| Benzimidazole SCHEMBL8901469 | 0.86 | SMN1; SMN2 (0.57) | KDM4ESMN1; SMN2RAB9AALDH1A1HPGD | |
| Benzimidazole SCHEMBL2334176 | 0.86 | PRKCI (0.50) | KDM4ESMN1; SMN2RAB9AALDH1A1HPGD | |
| Benzimidazole SCHEMBL11810774 | 0.86 | KDM4E (0.46) | KDM4ESMN1; SMN2RAB9AALDH1A1HPGD | |
| Terephthalamide SCHEMBL29216571 | 0.86 | PARP1 (0.54) | KDM4ESMN1; SMN2RAB9AALDH1A1HPGD | |
| Benzimidazole SCHEMBL4306997 | 0.86 | CTNNB1 (0.47) | KDM4ESMN1; SMN2RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873346-A | BRONCHODILATORS, TREATMENT OF ASTHMA | THE UPJOHN COMPANY (US) | 1989-10-10 | — | — | US | disclosed |