Acridine

Acridine

SCHEMBL37657

N=C=S.c1ccc2nc3ccccc3cc2c1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
HPGD P15428 3/20 0.71
MAPT P10636 3/20 0.71
GLA P06280 2/20 0.71
ACHE P22303 1/20 0.71
HTR3A P46098 1/20 0.52
NQO2 P16083 2/20 0.48
KDM4E B2RXH2 3/20 0.45
GAA P10253 3/20 0.45
KMT2A Q03164 3/20 0.45
NPC1 O15118 3/20 0.45
POLB P06746 2/20 0.45
RAB9A P51151 2/20 0.45
LMNA P02545 1/20 0.45
PTBP1 P26599 1/20 0.45
RCE1 Q9Y256 1/20 0.45
TDP1 Q9NUW8 1/20 0.42
STAT3 P40763 1/20 0.42
PDE10A Q9Y233 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acridine SCHEMBL1006962 1.00 ALDH1A1 (0.71) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL28002752 0.86 ALDH1A1 (0.71) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL10533085 0.86 ALDH1A1 (0.71) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL1772714 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL4972293 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL29352289 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL8339 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL3045498 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL1551975 0.82 ALDH1A1 (0.94) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL2394207 0.82 ALDH1A1 (0.94) ALDH1A1HPGDMAPTGLAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4279 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059144-A1 DYNAMIC NANOMECHANICAL AMPLIFICATION ANTENNA AND USES SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2025-03-20 WO claimed
US-11725227-B2 Devices and methods for examining drug effects on microorganisms ESSENLIX CORPORATION (US) 2023-08-15 US claimed
US-20220237930-A1 CELL AGE CLASSIFICATION AND DRUG SCREENING FOUNTAIN THERAPEUTICS INC (US) 2022-07-28 US claimed
US-20210275693-A1 MODIFIED WOUND DRESSINGS CONVATEC TECHNOLOGIES INC. 2021-09-09 US claimed
CN-112689758-A Device and method for examining the effect of a drug on microorganisms ESSENLIX公司 2021-04-20 CN claimed
US-10961571-B2 Polymerase assay with a FRET substrate Life Technologies Corporation (US) 2021-03-30 US claimed
US-20200399675-A1 DEVICES AND METHODS FOR EXAMINING DRUG EFFECTS ON MICROORGANISMS ESSENLIX CORPORATION (US) 2020-12-24 US claimed
US-10605805-B2 Device and system for analyzing a sample, particularly blood, as well as methods of using the same ESSENLIX CORPORATION (US) 2020-03-31 US claimed
US-20190307904-A1 MODIFIED WOUND DRESSINGS CONVATEC TECHNOLOGIES INC (US) 2019-10-10 US claimed
EP-3541960-A2 METHODS AND DEVICES FOR DETECTING HEPATITIS C VIRUS Quest Diagnostics Investments LLC (US) 2019-09-25 EP claimed
EP-1067134-A2 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOTRONICS, INC. (US) 2001-01-10 EP claimed
US-6162603-A Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOGEN, INC. (US) 2000-12-19 US claimed
US-5565322-A PHOTOELECTRIC DEVICES; DETECTORS; MEDICAL DIAGNOSIS NANOGEN, INC. (US) 1996-10-15 US claimed
US-5532129-A Self-organizing molecular photonic structures based on chromophore- and fluorophore-containing polynucleotides and methods of their use ENTERPRISE PARTNERS II, L.P. (US) 1996-07-02 US claimed
EP-0620822-A4 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM. NANOTRONICS INC (US) 1996-01-10 EP claimed
EP-0620822-A1 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM NANOTRONICS, INC. (US) 1994-10-26 EP claimed
EP-0300037-B1 CELL SCREENING METHODS RICHMOND CELL SCREENING LIMITED (GB) 1993-09-01 EP claimed
WO-1993009128-A1 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM NANOTRONICS, INC. (US) 1993-05-13 WO claimed
EP-0300037-A1 CELL SCREENING METHODS. RICHMOND CELL SCREENING LTD (GB) 1989-01-25 EP claimed
WO-1988005908-A1 CELL SCREENING, APPARATUS AND METHODS RICHMOND CELL SCREENING LIMITED (GB) 1988-08-11 WO claimed