Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 12/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 8/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8748944 | 0.98 | MEN1 (0.51) | MEN1KMT2APOLBPTGER4PTGER3 | |
| SCHEMBL8761679 | 0.98 | MEN1 (0.51) | MEN1KMT2APOLBPTGER4PTGER3 | |
| SCHEMBL3425106 | 0.98 | MEN1 (0.51) | MEN1KMT2APOLBPTGER4PTGER3 | |
| SCHEMBL8749215 | 0.98 | MEN1 (0.51) | MEN1KMT2APOLBPTGER4PTGER3 | |
| SCHEMBL8748862 | 0.98 | MEN1 (0.51) | MEN1KMT2APOLBPTGER4PTGER3 | |
| SCHEMBL8761610 | 0.98 | MEN1 (0.51) | MEN1KMT2APOLBPTGER4PTGER3 | |
| SCHEMBL8754825 | 0.98 | MEN1 (0.51) | MEN1KMT2APOLBPTGER4PTGER3 | |
| SCHEMBL8761736 | 0.98 | MEN1 (0.51) | MEN1KMT2APOLBPTGER4PTGER3 | |
| SCHEMBL242586 | 0.98 | MEN1 (0.51) | MEN1KMT2APOLBPTGER4PTGER3 | |
| SCHEMBL8748934 | 0.98 | MEN1 (0.51) | MEN1KMT2APOLBPTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989011275-A1 | PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC AGENTS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-11-30 | — | — | WO | disclosed |