Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | PMM2 | O15305 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9812155 | 0.82 | MAPT (0.40) | MAPK1KMT2AGAAMEN1TDP1 | |
| SCHEMBL11845472 | 0.75 | GRM5 (0.36) | MAPK1KMT2AGAAMEN1 | |
| SCHEMBL10534035 | 0.75 | GRM5 (0.36) | MAPK1KMT2AGAAMEN1 | |
| SCHEMBL10883936 | 0.70 | GRM5 (0.39) | MAPK1KMT2AGAATDP1CYP1A2 | |
| SCHEMBL10883933 | 0.70 | GRM5 (0.39) | MAPK1KMT2AGAATDP1CYP1A2 | |
| SCHEMBL10534530 | 0.70 | ALDH1A1 (0.40) | MAPK1KMT2AGAAMEN1NPSR1 | |
| SCHEMBL11539280 | 0.69 | CTDSP1 (0.44) | MAPK1KMT2AGAATDP1CYP1A2 | |
| SCHEMBL10533523 | 0.66 | ALDH1A1 (0.41) | MAPK1KMT2AGAATDP1CYP3A4 | |
| SCHEMBL13910280 | 0.63 | — | — | |
| SCHEMBL11215092 | 0.61 | HPGD (0.40) | MAPK1KMT2AMEN1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989004595-A2 | ECTOPARASITICIDES | THE UPJOHN COMPANY (US) | 1989-06-01 | — | — | WO | disclosed |