Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534035 | 1.00 | GRM5 (0.36) | GRM5CNR1CNR2MAPTGAA | |
| SCHEMBL9812155 | 0.82 | MAPT (0.40) | MAPTGAAMAPK1HTTLMNA | |
| SCHEMBL9812153 | 0.82 | MAPT (0.40) | MAPTGAAMAPK1HTTLMNA | |
| SCHEMBL11850918 | 0.76 | SIGMAR1 (0.38) | CNR1CNR2MAPTGAALMNA | |
| SCHEMBL11215376 | 0.76 | SIGMAR1 (0.38) | CNR1CNR2MAPTGAALMNA | |
| SCHEMBL11215377 | 0.76 | SIGMAR1 (0.38) | CNR1CNR2MAPTGAALMNA | |
| SCHEMBL11157294 | 0.75 | SMN1; SMN2 (0.37) | CNR1CNR2MAPTGAAMAPK1 | |
| SCHEMBL10535049 | 0.75 | MAPK1 (0.39) | GAAMAPK1MEN1KMT2A | |
| SCHEMBL11249907 | 0.70 | MAPT (0.43) | MAPTGAAMAPK1HTTTTR | |
| SCHEMBL13910280 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3967965-A | HETEROCYCLIC UREAS | FUJI PHOTO FILM CO., LTD. (JA) | 1976-07-06 | — | — | US | disclosed |