SCHEMBL1053508

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1051458	0.92	MAP2K1 (0.43)	MAP2K1PTGER1BRAFSGMS2
	SCHEMBL1053834	0.91	FABP3 (0.53)	FABP3FABP4FABP5MAP2K1PTGER1
	SCHEMBL416210	0.91	FABP3 (0.42)	FABP3FABP4FABP5HPDMAP2K1
	SCHEMBL1053819	0.90	FABP3 (0.41)	FABP3FABP4FABP5HPDMAP2K1
	SCHEMBL1053901	0.90	FABP3 (0.41)	FABP3FABP4FABP5HPDMAP2K1
	SCHEMBL1054297	0.89	SGMS2 (0.46)	MAP2K1CYP1A2CYP2C19BRAFSGMS2
	SCHEMBL1052298	0.89	FABP3 (0.40)	FABP3FABP4FABP5HPDPTGER1
	SCHEMBL1051521	0.87	HPD (0.39)	FABP3FABP4FABP5HPDPTGER1
	SCHEMBL414969	0.87	PAK1 (0.42)	FABP3FABP4FABP5HPDMAP2K1
	SCHEMBL416151	0.86	L3MBTL1 (0.46)	MAP2K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.