Acetone

Acetone

SCHEMBL10535239

CC(C)=O.CCCCC(CC)Cc1c(CC(CC)CCCC)c(C(=O)O)c(C(=O)O)c(CC(CC)CCCC)c1C(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.41
CYP3A4 P08684 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
ATM Q13315 1/20 0.41
CA2 P00918 5/20 0.41
ALDH1A1 P00352 6/20 0.40
MAPK1 P28482 4/20 0.38
CA1 P00915 1/20 0.37
LMNA P02545 4/20 0.37
HTT P42858 2/20 0.36
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSD17B10 Q99714 1/20 0.36
GLA P06280 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RECQL P46063 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29523183 0.97 TSHR (0.44) TSHRCYP3A4TDP1ATMCA2
SCHEMBL108345 0.97 TSHR (0.44) TSHRCYP3A4TDP1ATMCA2
SCHEMBL7878129 0.93 CA2 (0.46) TSHRCYP3A4TDP1ATMCA2
SCHEMBL8959367 0.93 CA2 (0.46) TSHRCYP3A4TDP1ATMCA2
SCHEMBL14989251 0.90 CA2 (0.44) TSHRCYP3A4TDP1ATMCA2
SCHEMBL23646642 0.88 CA2 (0.42) TSHRCYP3A4TDP1ATMCA2
SCHEMBL10774869 0.87 CA2 (0.39) TSHRCYP3A4TDP1ATMCA2
Benzoic Acid SCHEMBL15918863 0.86 ALDH1A1 (0.47) TSHRCYP3A4CA2ALDH1A1MAPK1
SCHEMBL25280291 0.84 ALDH1A1 (0.55) TSHRCYP3A4TDP1ATMCA2
SCHEMBL16965873 0.82 POLB (0.33) HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4799935-A EVAPORATION OF LOWER BOILING SOLVENT BURLINGTON INDUSTRIES, INC. (US) 1989-01-24 US disclosed