SCHEMBL8959367

SCHEMBL8959367

CCCCC(CC)Cc1c(C(=O)O)c(CC(CC)CCCC)c(C(=O)O)c(CC(CC)CCCC)c1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.46
ALDH1A1 P00352 4/20 0.45
MAPK1 P28482 1/20 0.42
TSHR P16473 4/20 0.42
CYP3A4 P08684 4/20 0.42
TDP1 Q9NUW8 2/20 0.42
ATM Q13315 1/20 0.42
CA1 P00915 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.39
GLA P06280 1/20 0.39
HTT P42858 1/20 0.39
GPR84 Q9NQS5 3/20 0.37
FFAR1 O14842 1/20 0.37
LMNA P02545 1/20 0.37
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37
SLC1A1 P43005 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29523183 0.96 TSHR (0.44) CA2ALDH1A1MAPK1TSHRCYP3A4
SCHEMBL108345 0.96 TSHR (0.44) CA2ALDH1A1MAPK1TSHRCYP3A4
SCHEMBL7878129 0.96 CA2 (0.46) CA2ALDH1A1MAPK1TSHRCYP3A4
Acetone SCHEMBL10535239 0.93 TSHR (0.41) CA2ALDH1A1MAPK1TSHRCYP3A4
SCHEMBL14989251 0.89 CA2 (0.44) CA2ALDH1A1MAPK1TSHRCYP3A4
SCHEMBL23646642 0.87 CA2 (0.42) CA2ALDH1A1MAPK1TSHRCYP3A4
SCHEMBL14989115 0.87 CA2 (0.41) CA2ALDH1A1MAPK1TSHRCYP3A4
SCHEMBL20920808 0.87 CA2 (0.41) CA2ALDH1A1MAPK1TSHRCYP3A4
SCHEMBL10774869 0.87 CA2 (0.39) CA2ALDH1A1MAPK1TSHRCYP3A4
Benzoic Acid SCHEMBL15918863 0.85 ALDH1A1 (0.47) CA2ALDH1A1MAPK1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1567470-B1 HYDROGENATION OF BENZENE POLYCARBOXYLIC ACIDS OR DERIVATIVES THEREOF EXXONMOBIL CHEM PATENTS INC (US) 2013-06-05 EP claimed
EP-0693254-A1 Gel formulations containing insecticides for vaporizer systems BAYER AG (DE) 1996-01-24 EP disclosed