Ethylene Glycol

Ethylene Glycol

SCHEMBL10536746

C=CCCC/C=C/COC/C=C/CCCC=C.OCCO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
TSHR P16473 2/20 0.32
LMNA P02545 2/20 0.31
MAPT P10636 2/20 0.31
USP2 O75604 1/20 0.31
CYP3A4 P08684 1/20 0.31
RECQL P46063 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LPAR3 Q9UBY5 2/20 0.31
LPAR2 Q9HBW0 1/20 0.31
ABCC4 O15439 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL534005 0.91 TSHR (0.38) ALDH1A1TSHRLMNAMAPTUSP2
SCHEMBL2286811 0.91 TSHR (0.38) ALDH1A1TSHRLMNAMAPTUSP2
SCHEMBL318538 0.88 TSHR (0.35) ALDH1A1TSHRLPAR3LPAR2
SCHEMBL318539 0.88 TSHR (0.35) ALDH1A1TSHRLPAR3LPAR2
SCHEMBL10883939 0.86 TSHR (0.35) ALDH1A1TSHR
SCHEMBL27517883 0.86 TSHR (0.40) ALDH1A1TSHRLMNAMAPTUSP2
SCHEMBL874849 0.84 MEN1 (0.41) TSHRMAPTLPAR3LPAR2
SCHEMBL875224 0.84 MEN1 (0.41) TSHRMAPTLPAR3LPAR2
SCHEMBL876089 0.84 MEN1 (0.41) TSHRMAPTLPAR3LPAR2
SCHEMBL875145 0.84 MEN1 (0.41) TSHRMAPTLPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4843180-A Preparation of ethers THE DOW CHEMICAL COMPANY (US) 1989-06-27 US disclosed