SCHEMBL318539

SCHEMBL318539

C=CCCCC=CCOCCO

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
MAPK1 P28482 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LPAR3 Q9UBY5 2/20 0.32
LPAR2 Q9HBW0 1/20 0.32
ESR1 P03372 1/20 0.30
ALDH1A1 P00352 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL318538 1.00 TSHR (0.35) TSHRMAPK1MEN1KMT2ALPAR3
SCHEMBL876089 0.96 MEN1 (0.41) TSHRMAPK1MEN1KMT2ALPAR3
SCHEMBL874849 0.96 MEN1 (0.41) TSHRMAPK1MEN1KMT2ALPAR3
SCHEMBL876101 0.96 MEN1 (0.41) TSHRMAPK1MEN1KMT2ALPAR3
SCHEMBL875224 0.96 MEN1 (0.41) TSHRMAPK1MEN1KMT2ALPAR3
SCHEMBL875145 0.96 MEN1 (0.41) TSHRMAPK1MEN1KMT2ALPAR3
Ethylene Glycol SCHEMBL10536746 0.88 ALDH1A1 (0.32) TSHRLPAR3LPAR2ALDH1A1
SCHEMBL10536751 0.87 TSHR (0.35) TSHRMEN1KMT2ALPAR3LPAR2
SCHEMBL10955085 0.85 TSHR (0.33) TSHRLPAR3LPAR2ALDH1A1
SCHEMBL534005 0.83 TSHR (0.38) TSHRLPAR3LPAR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2321254-B1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD EVONIK ROEHM GMBH (DE) 2014-07-30 EP disclosed
US-8420709-B2 Coating composition, (meth)acrylic polymer and monomer mixture for producing the (meth)acrylic polymer EVONIK RÖHM GMBH (DE) 2013-04-16 US disclosed
US-8415422-B2 (Meth)acrylate monomer, polymer and coating agent EVONIK RÖHM GMBH (DE) 2013-04-09 US disclosed
WO-2012038197-A1 COATING AGENT HAVING (METH)ACRYLIC POLYMERS AND COALESCENCE ADDITIVES EVONIK RÖHM GMBH (DE) 2012-03-29 WO disclosed
EP-2414412-A1 (METH)ACRYLATE POLYMER, COATING AGENT, METHOD FOR PRODUCING A COATING, AND COATED OBJECT Evonik Röhm GmbH (DE) 2012-02-08 EP disclosed
EP-2414462-A1 COATING COMPOSITION, (METH)ACRYL-POLYMER AND MONOMER MIXTURE FOR PRODUCING SAID (METH)ACRYL-POLYMER Evonik Röhm GmbH (DE) 2012-02-08 EP disclosed
EP-2414413-A1 POLYFUNCTIONAL (METH)ACRYLIC POLYMER, COATING COMPOSITION, PROCESS FOR PRODUCING A COATING AND COATED ARTICLE Evonik Röhm GmbH (DE) 2012-02-08 EP disclosed
US-20120016071-A1 POLYFUNCTIONAL (METH)ACRYLIC POLYMER, COATING COMPOSITION, PROCESS FOR PRODUCING A COATING AND COATED ARTICLE EVONIK ROEHM GMBH (DE) 2012-01-19 US disclosed
WO-2012004160-A1 COMPOSITION FOR PRODUCING POLYMERS, (METH)ACRYLIC POLYMER, COATING AGENT, AND COATING EVONIK RÖHM GMBH (DE) 2012-01-12 WO disclosed
US-20110318595-A1 COATING COMPOSITION, (METH)ACRYLIC POLYMER AND MONOMER MIXTURE FOR PRODUCING THE (METH)ACRYLIC POLYMER EVONIK ROEHM GMBH (DE) 2011-12-29 US disclosed
EP-1201657-B1 Imidazolium salts and the use of these ionic liquids as a solvent and as a catalyst CENTRE NAT RECH SCIENT (FR) 2004-05-06 EP disclosed
US-20040026666-A1 Imidazolium salts and their use of these ionic liquids as a solvent CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2004-02-12 US disclosed
EP-1328518-A1 IMIDAZOLIUM SALTS AND THE USE OF THESE IONIC LIQUIDS AS A SOLVENT CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2003-07-23 EP disclosed
US-6525228-B2 Reacting a conjugated diene with a compound containing active hydrogen in the presence of a cataylst system comprising a transition metal compound, a phosphorus containing compound and atleast one salt CELANESE CHEMICALS EUROPE GMBH (DE) 2003-02-25 US disclosed
US-20020091281-A1 Process of telomerizing conjugated dienes CELANESE CHEMICALS EUROPE GMBH (DE) 2002-07-11 US disclosed
EP-1201634-A1 Process of telomerizing conjugated dienes Celanese Chemicals Europe GmbH (DE) 2002-05-02 EP disclosed
EP-1201657-A1 Imidazolium salts and the use of these ionic liquids as a solvent and as a catalyst CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2002-05-02 EP disclosed
WO-2002034722-A1 IMIDAZOLIUM SALTS AND THEIR USE OF THESE IONIC LIQUIDS AS A SOLVENT CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2002-05-02 WO disclosed
US-4843180-A Preparation of ethers THE DOW CHEMICAL COMPANY (US) 1989-06-27 US disclosed
US-4334117-A DIMERIZATION OF BUTADIENE/1,3-/ AND ISOPRENE KURARAY CO., LTD. (JP) 1982-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020091281-A1 Process of telomerizing conjugated dienes TELO2, TERT, PCNA TSHR 2595/4885MAPK1 1446/4885MEN1 143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.