SCHEMBL318538

SCHEMBL318538

C=CCCC/C=C/COCCO

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
MAPK1 P28482 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LPAR3 Q9UBY5 2/20 0.32
LPAR2 Q9HBW0 1/20 0.32
ESR1 P03372 1/20 0.30
ALDH1A1 P00352 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL318539 1.00 TSHR (0.35) TSHRMAPK1MEN1KMT2ALPAR3
SCHEMBL876089 0.96 MEN1 (0.41) TSHRMAPK1MEN1KMT2ALPAR3
SCHEMBL874849 0.96 MEN1 (0.41) TSHRMAPK1MEN1KMT2ALPAR3
SCHEMBL876101 0.96 MEN1 (0.41) TSHRMAPK1MEN1KMT2ALPAR3
SCHEMBL875224 0.96 MEN1 (0.41) TSHRMAPK1MEN1KMT2ALPAR3
SCHEMBL875145 0.96 MEN1 (0.41) TSHRMAPK1MEN1KMT2ALPAR3
Ethylene Glycol SCHEMBL10536746 0.88 ALDH1A1 (0.32) TSHRLPAR3LPAR2ALDH1A1
SCHEMBL10536751 0.87 TSHR (0.35) TSHRMEN1KMT2ALPAR3LPAR2
SCHEMBL10955085 0.85 TSHR (0.33) TSHRLPAR3LPAR2ALDH1A1
SCHEMBL534005 0.83 TSHR (0.38) TSHRLPAR3LPAR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2321254-B1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD EVONIK ROEHM GMBH (DE) 2014-07-30 EP disclosed
US-8420709-B2 Coating composition, (meth)acrylic polymer and monomer mixture for producing the (meth)acrylic polymer EVONIK RÖHM GMBH (DE) 2013-04-16 US disclosed
US-8415422-B2 (Meth)acrylate monomer, polymer and coating agent EVONIK RÖHM GMBH (DE) 2013-04-09 US disclosed
WO-2012038197-A1 COATING AGENT HAVING (METH)ACRYLIC POLYMERS AND COALESCENCE ADDITIVES EVONIK RÖHM GMBH (DE) 2012-03-29 WO disclosed
EP-2414412-A1 (METH)ACRYLATE POLYMER, COATING AGENT, METHOD FOR PRODUCING A COATING, AND COATED OBJECT Evonik Röhm GmbH (DE) 2012-02-08 EP disclosed
EP-2414462-A1 COATING COMPOSITION, (METH)ACRYL-POLYMER AND MONOMER MIXTURE FOR PRODUCING SAID (METH)ACRYL-POLYMER Evonik Röhm GmbH (DE) 2012-02-08 EP disclosed
EP-2414413-A1 POLYFUNCTIONAL (METH)ACRYLIC POLYMER, COATING COMPOSITION, PROCESS FOR PRODUCING A COATING AND COATED ARTICLE Evonik Röhm GmbH (DE) 2012-02-08 EP disclosed
US-20120016071-A1 POLYFUNCTIONAL (METH)ACRYLIC POLYMER, COATING COMPOSITION, PROCESS FOR PRODUCING A COATING AND COATED ARTICLE EVONIK ROEHM GMBH (DE) 2012-01-19 US disclosed
WO-2012004160-A1 COMPOSITION FOR PRODUCING POLYMERS, (METH)ACRYLIC POLYMER, COATING AGENT, AND COATING EVONIK RÖHM GMBH (DE) 2012-01-12 WO disclosed
US-20110318595-A1 COATING COMPOSITION, (METH)ACRYLIC POLYMER AND MONOMER MIXTURE FOR PRODUCING THE (METH)ACRYLIC POLYMER EVONIK ROEHM GMBH (DE) 2011-12-29 US disclosed
WO-2010026204-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD EVONIK RÖHM GMBH (DE) 2010-03-11 WO disclosed
US-20070060713-A1 Reactive diluents in coating formulation BP CHEMICALS LIMITED (GB) 2007-03-15 US disclosed
US-20070060713-A1 Reactive diluents in coating formulation BP CHEMICALS LIMITED (GB) 2007-03-15 US disclosed
US-20070004825-A1 Reactive diluents THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2007-01-04 US disclosed
US-20070004825-A1 Reactive diluents THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2007-01-04 US disclosed
EP-1201657-B1 Imidazolium salts and the use of these ionic liquids as a solvent and as a catalyst CENTRE NAT RECH SCIENT (FR) 2004-05-06 EP disclosed
US-20040026666-A1 Imidazolium salts and their use of these ionic liquids as a solvent CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2004-02-12 US disclosed
EP-1328518-A1 IMIDAZOLIUM SALTS AND THE USE OF THESE IONIC LIQUIDS AS A SOLVENT CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2003-07-23 EP disclosed
EP-1201657-A1 Imidazolium salts and the use of these ionic liquids as a solvent and as a catalyst CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2002-05-02 EP disclosed
WO-2002034722-A1 IMIDAZOLIUM SALTS AND THEIR USE OF THESE IONIC LIQUIDS AS A SOLVENT CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2002-05-02 WO disclosed