Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875224 | 1.00 | MEN1 (0.41) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL876089 | 1.00 | MEN1 (0.41) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL876101 | 1.00 | MEN1 (0.41) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL874849 | 1.00 | MEN1 (0.41) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL318539 | 0.96 | TSHR (0.35) | MEN1KMT2ATSHRMAPK1LPAR3 | |
| SCHEMBL318538 | 0.96 | TSHR (0.35) | MEN1KMT2ATSHRMAPK1LPAR3 | |
| SCHEMBL10536751 | 0.88 | TSHR (0.35) | MEN1KMT2ATSHRLPAR3LPAR2 | |
| SCHEMBL823800 | 0.87 | MEN1 (0.44) | MEN1KMT2ATSHRMAPK1THRB | |
| Ethylene Glycol SCHEMBL10536746 | 0.84 | ALDH1A1 (0.32) | TSHRMAPTLPAR3LPAR2 | |
| Di(Hydroxyethyl)Ether SCHEMBL27680359 | 0.84 | TSHR (0.53) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038197-A1 | COATING AGENT HAVING (METH)ACRYLIC POLYMERS AND COALESCENCE ADDITIVES | EVONIK RÖHM GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |