Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10537438 | 0.87 | TGFBR1 (0.46) | CCR1CCR8GRM5HSP90AA1HSP90AB1 | |
| SCHEMBL10540409 | 0.85 | HSP90AA1 (0.54) | CCR1CCR8GRM5HSP90AA1HSP90AB1 | |
| SCHEMBL31127079 | 0.81 | CCR1 (0.58) | CCR1CCR8GRM5MAPK14TGFBR1 | |
| SCHEMBL2614974 | 0.81 | CCR1 (0.58) | CCR1CCR8GRM5HSP90AA1HSP90AB1 | |
| SCHEMBL2241672 | 0.81 | CCR1 (0.58) | CCR1CCR8GRM5MAPK14TGFBR1 | |
| SCHEMBL10539246 | 0.81 | PDE2A (0.40) | CCR1CCR8GRM5HSP90AA1HSP90AB1 | |
| SCHEMBL8951931 | 0.79 | CCR1 (0.47) | CCR1CCR8GRM5KMT2AMAPK14 | |
| SCHEMBL6588868 | 0.79 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1KMT2AMEN1CYP19A1 | |
| SCHEMBL2016378 | 0.78 | CCR1 (0.54) | CCR1CCR8GRM5KMT2AMAPK14 | |
| SCHEMBL10539809 | 0.77 | GRM5 (0.52) | CCR1CCR8GRM5MAPK14CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873248-A | Pyridinylpyrimidines having fungicidal activity | SUMITOMO CHEMICAL CO., LTD. (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0270362-A2 | Pyridinylpyrimidine derivatives, method for production thereof and a fungicide containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-06-08 | — | — | EP | disclosed |