Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP10 | Q14694 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10538633 | 0.90 | KMT2A (0.49) | HCAR3MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL10540661 | 0.80 | TDP1 (0.57) | HCAR3MAPTKDM4EKMT2AMEN1 | |
| Ethalfluralin SCHEMBL55014 | 0.78 | CYP3A4 (0.64) | HCAR3MAPTKMT2AMEN1ALDH1A1 | |
| Ethalfluralin SCHEMBL4899703 | 0.78 | CYP3A4 (0.64) | HCAR3MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10537929 | 0.77 | VCAM1 (0.46) | HCAR3MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL11364205 | 0.76 | VCAM1 (0.52) | HCAR3MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL10867828 | 0.76 | MAPK1 (0.46) | HCAR3MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11359453 | 0.75 | VCAM1 (0.49) | MAPTKDM4EKMT2AMEN1VCAM1 | |
| SCHEMBL10541235 | 0.75 | HCAR3 (0.47) | HCAR3MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL10540126 | 0.75 | HCAR3 (0.47) | HCAR3MAPTKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806151-A | ESTERIFICATION, THEN AMINATION OF 4-CHLORO-3,5-DINITRO-BENZOIC ACID; ACID CATALYST, SALT FORMATION OF EXCESS; FUNGICIDES, HERBICIDES | BUDAPESTI VEGYIMUVEK (HU) | 1989-02-21 | — | — | US | disclosed |