Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28421319 | 0.79 | ALOX15 (0.35) | ALOX15LMNAHSD17B10ALDH1A1 | |
| SCHEMBL5561661 | 0.79 | ALDH1A1 (0.38) | ALOX15LMNAHSD17B10ALDH1A1 | |
| SCHEMBL476015 | 0.77 | ALDH1A1 (0.41) | ALOX15LMNAHSD17B10TSHRBLM | |
| SCHEMBL22557964 | 0.77 | FFAR3 (0.35) | ALOX15ALDH1A1 | |
| SCHEMBL1759546 | 0.74 | ALDH1A1 (0.38) | ALOX15CYP2C19BLMALDH1A1 | |
| SCHEMBL476014 | 0.74 | TDP1 (0.33) | ALOX15 | |
| SCHEMBL4644510 | 0.72 | ALOX15 (0.31) | ALOX15ALDH1A1 | |
| SCHEMBL28370169 | 0.72 | HCAR2 (0.39) | ALOX15 | |
| SCHEMBL15843315 | 0.72 | ALOX15 (0.31) | ALOX15 | |
| SCHEMBL15843316 | 0.72 | ALOX15 (0.31) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4837349-A | Tertiary-butyldimethylsilyl carbamate derivative and process for producing the same | SUNTORY LIMITED (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0217243-A2 | Tertiary-butyldimethylsilyl carbamate derivative and process for producing the same | SUNTORY LIMITED (JP) | 1987-04-08 | — | — | EP | disclosed |