Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 11/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769330 | 0.82 | ADRB2 (0.44) | ADRB2ADRB1 | |
| SCHEMBL10539606 | 0.80 | ADRB2 (0.55) | ADRB2ADRB3ADRB1CASR | |
| Hydrochloric Acid SCHEMBL10540907 | 0.79 | ADRB2 (0.55) | ADRB2ADRB3ADRB1CASR | |
| SCHEMBL10539169 | 0.76 | ADRB2 (0.60) | ADRB2ADRB3ADRB1CASR | |
| Hydrochloric Acid SCHEMBL10539540 | 0.74 | ADRB2 (0.55) | ADRB2ADRB3ADRB1CASR | |
| SCHEMBL20832742 | 0.72 | SMN1; SMN2 (0.40) | ADRB2ADRB3ADRB1 | |
| SCHEMBL20819399 | 0.72 | SMN1; SMN2 (0.40) | ADRB2ADRB3ADRB1 | |
| SCHEMBL6479693 | 0.72 | ADRB2 (0.67) | ADRB2ADRB3ADRB1 | |
| SCHEMBL9769158 | 0.71 | CCNE1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL20819389 | 0.71 | SMN1; SMN2 (0.39) | ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816457-A | HYPOTENSIVE AGENTS, BRONCHODILATORS, EYES | MERCK & CO., INC., A CORP. OF NJ | 1989-03-28 | — | — | US | disclosed |