Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23484567 | 0.92 | TDP1 (0.61) | TDP1LMNATSHRADRB2ADRB1 | |
| SCHEMBL5710092 | 0.85 | TDP1 (0.61) | TDP1LMNATSHRADRB2ADRB1 | |
| SCHEMBL8341763 | 0.85 | TDP1 (0.61) | TDP1LMNATSHRADRB2ADRB1 | |
| SCHEMBL1104298 | 0.84 | ALDH1A1 (0.54) | TDP1LMNATSHRNPC1L3MBTL1 | |
| SCHEMBL9107131 | 0.84 | TSHR (0.49) | TDP1LMNATSHRNPC1L3MBTL1 | |
| SCHEMBL10537051 | 0.83 | TDP1 (0.59) | TDP1LMNATSHRADRB2ADRB1 | |
| SCHEMBL23484459 | 0.81 | TDP1 (0.65) | TDP1LMNATSHRADRB2ADRB1 | |
| SCHEMBL8340553 | 0.80 | TDP1 (0.59) | TDP1LMNATSHRADRB2ADRB1 | |
| SCHEMBL3342492 | 0.78 | TDP1 (0.61) | TDP1LMNATSHRADRB2ADRB1 | |
| SCHEMBL6053597 | 0.78 | MAPK1 (0.65) | TDP1LMNATSHRADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886843-A | CALCIUM HYDROXIDE CEMENT CHARACTERISTICS AND LIGHT CURE CHARACTERISTICS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-12-12 | — | — | US | disclosed |