Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2003037 | 0.89 | TSHR (0.55) | TDP1LMNATSHRALDH1A1NPC1 | |
| SCHEMBL23484459 | 0.85 | TDP1 (0.65) | TDP1LMNATSHRALDH1A1NPC1 | |
| SCHEMBL9247458 | 0.82 | ADRB2 (0.50) | TDP1LMNATSHRALDH1A1NPC1 | |
| SCHEMBL8567872 | 0.82 | ALDH1A1 (0.59) | TDP1TSHRALDH1A1NPC1KMT2A | |
| SCHEMBL8442126 | 0.82 | TDP1 (0.61) | TDP1LMNATSHRALDH1A1NPC1 | |
| SCHEMBL8341763 | 0.82 | TDP1 (0.61) | TDP1LMNATSHRALDH1A1NPC1 | |
| SCHEMBL23484567 | 0.82 | TDP1 (0.61) | TDP1LMNATSHRALDH1A1NPC1 | |
| SCHEMBL5710092 | 0.82 | TDP1 (0.61) | TDP1LMNATSHRALDH1A1NPC1 | |
| SCHEMBL10397449 | 0.81 | TDP1 (0.69) | TDP1LMNATSHRALDH1A1NPC1 | |
| SCHEMBL23484313 | 0.81 | TDP1 (0.59) | TDP1LMNATSHRALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858503-B1 | TOPICAL GELS COMPOSITIONS | GREEN MONIQUE RENATA (US) | 2013-09-04 | — | — | EP | disclosed |
| US-20100158993-A1 | Topical Gel Compositions | ISW GROUP, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| EP-1858503-A1 | TOPICAL GELS COMPOSITIONS | ISW Group Inc. (US) | 2007-11-28 | — | — | EP | disclosed |
| US-20070053984-A1 | Topical gels compositions | SPANN-WADE MONIQUE | 2007-03-08 | — | — | US | disclosed |
| WO-2006096360-A1 | TOPICAL GELS COMPOSITIONS | ISW GROUP, INC. (US) | 2006-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070053984-A1 | Topical gels compositions | PTGES, PTGER1, S100A8 | TDP1 860/4885LMNA 1759/4885TSHR 4872/4885 |
| US-20100158993-A1 | Topical Gel Compositions | PTGES, PTGER1, PTGS1 | TDP1 1003/4885LMNA 1733/4885TSHR 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.