Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341763 | 0.89 | TDP1 (0.61) | TDP1TSHRLMNAADRB2ADRB1 | |
| SCHEMBL23484567 | 0.89 | TDP1 (0.61) | TDP1TSHRLMNAADRB2ADRB1 | |
| SCHEMBL204881 | 0.89 | TSHR (0.61) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL23484459 | 0.85 | TDP1 (0.65) | TDP1TSHRLMNAADRB2ADRB1 | |
| SCHEMBL10539768 | 0.85 | TDP1 (0.56) | TDP1TSHRLMNAADRB2ADRB1 | |
| SCHEMBL8340553 | 0.84 | TDP1 (0.59) | TDP1TSHRLMNAADRB2ADRB1 | |
| SCHEMBL5663440 | 0.83 | ADRB2 (0.56) | TDP1TSHRLMNAADRB2ADRB1 | |
| SCHEMBL6911577 | 0.82 | TSHR (0.75) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL7633775 | 0.82 | ALDH1A1 (0.59) | TDP1TSHRLMNAALDH1A1L3MBTL1 | |
| SCHEMBL8442126 | 0.82 | TDP1 (0.61) | TDP1TSHRLMNAADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2772523-B1 | REVERSIBLY THERMOCHROMIC COMPOSITION | PILOT CORPORATION KK (JP) | 2018-11-28 | — | — | EP | disclosed |
| US-20140291585-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |
| EP-2772523-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION | Kabushiki Kaisha Pilot Corporation (JP) | 2014-09-03 | — | — | EP | disclosed |
| EP-1179435-B1 | Reversible thermochromic composition having improved light-fastness and product comprising same | PILOT INK CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-6638620-B2 | Discoloration sensitivity | THE PILOT INK CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| EP-1179435-A1 | Reversible thermochromic composition having improved light-fastness and product comprising same | The Pilot Ink Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |