Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.67 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.67 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.64 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibemethine SCHEMBL276863 | 1.00 | ALDH1A1 (0.70) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| Dibemethine SCHEMBL2139708 | 0.97 | ALDH1A1 (0.67) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL22305213 | 0.92 | KDM4E (0.61) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL11278307 | 0.89 | ALDH1A1 (0.64) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL7055109 | 0.89 | CARM1 (0.75) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL10194246 | 0.88 | CYP2C19 (0.61) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL8251052 | 0.88 | TP53 (0.64) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL355111 | 0.87 | TSHR (0.61) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| SCHEMBL21268450 | 0.86 | ALDH1A1 (0.63) | ALDH1A1TSHRCARM1PRMT6PRMT8 | |
| Dibemethine SCHEMBL3425329 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TSHRCARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801715-A | HYPOGLYCEMIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-31 | — | — | US | disclosed |