Dibemethine

Dibemethine

SCHEMBL276863

CN(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.70
TSHR P16473 2/20 0.70
CARM1 Q86X55 1/20 0.67
PRMT6 Q96LA8 1/20 0.67
PRMT8 Q9NR22 1/20 0.67
SMN1; SMN2 Q16637 3/20 0.65
KDM4E B2RXH2 3/20 0.65
LMNA P02545 3/20 0.64
USP2 O75604 1/20 0.64
CYP3A4 P08684 1/20 0.64
MAOA P21397 1/20 0.64
MAOB P27338 1/20 0.64
PYCR1 P32322 1/20 0.64
AOC3 Q16853 1/20 0.64
BLM P54132 1/20 0.61
SIGMAR1 Q99720 1/20 0.59
GAA P10253 2/20 0.57
MAPT P10636 1/20 0.57
POLB P06746 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibemethine SCHEMBL10542007 1.00 ALDH1A1 (0.70) ALDH1A1TSHRCARM1PRMT6PRMT8
Dibemethine SCHEMBL2139708 0.97 ALDH1A1 (0.67) ALDH1A1TSHRCARM1PRMT6PRMT8
SCHEMBL22305213 0.92 KDM4E (0.61) ALDH1A1TSHRCARM1PRMT6PRMT8
SCHEMBL11278307 0.89 ALDH1A1 (0.64) ALDH1A1TSHRCARM1PRMT6PRMT8
SCHEMBL7055109 0.89 CARM1 (0.75) ALDH1A1TSHRCARM1PRMT6PRMT8
SCHEMBL10194246 0.88 CYP2C19 (0.61) ALDH1A1TSHRCARM1PRMT6PRMT8
SCHEMBL8251052 0.88 TP53 (0.64) ALDH1A1TSHRCARM1PRMT6PRMT8
SCHEMBL355111 0.87 TSHR (0.61) ALDH1A1TSHRCARM1PRMT6PRMT8
SCHEMBL21268450 0.86 ALDH1A1 (0.63) ALDH1A1TSHRCARM1PRMT6PRMT8
Dibemethine SCHEMBL3425329 0.86 ALDH1A1 (0.54) ALDH1A1TSHRCARM1PRMT6PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1879 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4352449-B1 PROJECTILE PAYLOAD FOR TRAINING AMMUNITION WITH MULTI-SPECTRAL OUTPUT CYALUME TECH INC (US) 2025-05-07 EP claimed
CN-119529795-A Foam sand-fixing agent and preparation method and application thereof 中国石油天然气股份有限公司 2025-02-28 CN claimed
EP-4352449-A2 PROJECTILE PAYLOAD FOR TRAINING AMMUNITION WITH MULTI-SPECTRAL OUTPUT Cyalume Technologies, Inc (US) 2024-04-17 EP claimed
US-11940253-B2 Projectile payload for training ammunition with multi-spectral output CYALUME TECHNOLOGIES, INC. (US) 2024-03-26 US claimed
CN-116535988-A Barrier adhesive film for flexible circuit board and production method thereof 四川三益电子新材料有限公司 2023-08-04 CN claimed
CN-111116528-B Method for producing aromatic primary diamine 罗地亚经营管理公司 2023-08-01 CN claimed
WO-2023140886-A2 PROJECTILE PAYLOAD FOR TRAINING AMMUNITION WITH MULTI-SPECTRAL OUTPUT CYALUME TECHNOLOGIES, INC. (US) 2023-07-27 WO claimed
EP-4208467-A1 DIOL DESYMMETRIZATION BY NUCLEOPHILIC AROMATIC SUBSTITUTION Amgen Inc. (US) 2023-07-12 EP claimed
US-20230194226-A1 Projectile payload for training ammunition with multi-spectral output PNC BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2023-06-22 US claimed
CN-115184529-B Detection method of N-methylbenzylamine related substances 河北广祥制药有限公司 2023-05-02 CN claimed
EP-0924196-A1 Process for the alkylation of alkyl- or benzonitrile in the presence of trialkyl amines or phosphines Hoechst Marion Roussel Deutschland GmbH (DE) 1999-06-23 EP claimed
EP-0752984-B1 PROCESS FOR THE PREPARATION OF CYCLOHEXYL-AZETIDINONES GLAXO WELLCOME SPA (IT) 1999-05-19 EP claimed
EP-0752984-A1 PROCESS FOR THE PREPARATION OF CYCLOHEXYL-AZETIDINONES GLAXO WELLCOME S.p.A. (IT) 1997-01-15 EP claimed
WO-1995026333-A1 PROCESS FOR THE PREPARATION OF CYCLOHEXYL-AZETIDINONES GLAXO WELLCOME S.P.A. (IT) 1995-10-05 WO claimed
EP-0383089-B1 Cold curing reactive resin blend and its use BAYER AG (DE) 1994-04-06 EP claimed
US-5084544-A Reaction of polyepoxides and polyisocyanates to form polyurethanes BAYER AKTIENGESELLSCHAFT (DE) 1992-01-28 US claimed
EP-0383089-A2 Cold curing reactive resin blend and its use BAYER AG (DE) 1990-08-22 EP claimed
US-4224416-A Degradable plastic composition containing amine OWENS-ILLINOIS, INC. (US) 1980-09-23 US claimed
US-4219626-A Accelerators for radical polymerization reactions with initiators free from peroxide groups BAYER AKTIENGESELLSCHAFT (DE) 1980-08-26 US claimed
US-4056547-A FROM AN ALKALI METAL OR AMMONIUM CYANATE AND A BENZYL CHLORIDE, CATALYST KAO SOAP CO., LTD. (JA) 1977-11-01 US claimed