Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3166061 | 0.81 | ERCC5 (0.62) | ERCC5FEN1KMT2ANPC1RAB9A | |
| SCHEMBL17526417 | 0.77 | NPC1 (0.46) | ERCC5FEN1ALDH1A1ALOX12KMT2A | |
| SCHEMBL13163159 | 0.74 | HPGD (0.58) | ALDH1A1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL101601 | 0.72 | TSHR (0.63) | ERCC5FEN1ALDH1A1ALOX12KMT2A | |
| SCHEMBL8701488 | 0.72 | ALDH1A1 (0.45) | ERCC5FEN1ALDH1A1ALOX12KMT2A | |
| SCHEMBL29702037 | 0.72 | TSHR (0.63) | ERCC5FEN1ALDH1A1ALOX12KMT2A | |
| SCHEMBL29716616 | 0.72 | ALDH1A1 (0.45) | ERCC5FEN1ALDH1A1ALOX12KMT2A | |
| SCHEMBL13468195 | 0.71 | KMT2A (0.58) | ERCC5FEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL15018447 | 0.71 | TSHR (0.61) | ALDH1A1ALOX12KMT2AKDM4EMAPT | |
| SCHEMBL8328257 | 0.71 | ERCC5 (0.40) | ERCC5FEN1ALDH1A1ALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4829076-A | CARDIOVASCULAR DISORDERS | ALKALOIDA VEGYESZETI GYAR (HU) | 1989-05-09 | — | — | US | disclosed |