Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15678965 | 0.82 | HPGD (0.53) | HPGDERCC5FEN1SMN1; SMN2KMT2A | |
| SCHEMBL3166061 | 0.80 | ERCC5 (0.62) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL10544754 | 0.77 | ERCC5 (0.46) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL19687548 | 0.74 | TSHR (0.50) | NPC1RAB9AHPGDLMNATSHR | |
| SCHEMBL13957399 | 0.74 | HPGD (0.41) | HPGDERCC5FEN1TSHRSMN1; SMN2 | |
| SCHEMBL18508975 | 0.74 | HPGD (0.41) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL13163159 | 0.72 | HPGD (0.58) | NPC1RAB9AHPGDLMNASMN1; SMN2 | |
| SCHEMBL22850233 | 0.72 | HPGD (0.42) | NPC1RAB9AHPGDERCC5FEN1 | |
| SCHEMBL20879355 | 0.72 | MAOA (0.42) | HPGDERCC5FEN1SMN1; SMN2 | |
| SCHEMBL9723735 | 0.71 | NPC1 (0.45) | NPC1RAB9AHPGDERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637384-B2 | Fullerene derivatives and their applications in organic photovoltaics | NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (HK) | 2017-05-02 | — | — | US | disclosed |
| US-20160039676-A1 | Fullerene Derivatives and Their Applications in Organic Photovoltaics | NANO AND ADVANCED MATERIALS INSTITUTE LIMITED (CN) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039676-A1 | Fullerene Derivatives and Their Applications in Organic Photovoltaics | CCND2, CCND1, CCND3 | NPC1 1318/4885RAB9A 735/4885HPGD 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.