Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29716616 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| Fluoride SCHEMBL28754865 | 0.98 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL27721374 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL11781549 | 0.80 | MAOA (0.39) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL12813963 | 0.80 | TSHR (0.38) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL6553295 | 0.78 | TSHR (0.50) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL212176 | 0.77 | LMNA (0.57) | ALDH1A1KDM4EMAPTKMT2ANPC1 | |
| Fluoride SCHEMBL28135103 | 0.77 | TSHR (0.48) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL19412006 | 0.76 | NPC1 (0.46) | ALDH1A1KDM4EMAPTALOX12KMT2A | |
| SCHEMBL2118326 | 0.76 | NPC1 (0.46) | ALDH1A1KDM4EMAPTALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230371508-A1 | COMPOSITIONS AND METHODS FOR KILLING INSECT AND NON-INSECT PESTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2023-11-23 | — | — | US | disclosed |
| US-11805776-B2 | Compositions and methods for killing insect and non-insect pests | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2023-11-07 | — | — | US | disclosed |
| US-20220183287-A1 | METHODS FOR KILLING PESTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2022-06-16 | — | — | US | disclosed |
| WO-2022125885-A1 | METHODS FOR KILLING PESTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2022-06-16 | — | — | WO | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-111517902-A | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2020-08-11 | — | — | CN | disclosed |
| WO-2020155595-A1 | AEROBIC OXIDATION SYSTEM CONTAINING SULFINIC ACID, SULFONIC ACID OR DERIVATIVES THEREOF AND PHOTOCATALYTIC OXIDATION METHOD THEREFOR | 清华大学 | 2020-08-06 | — | — | WO | disclosed |
| WO-2019143506-A1 | COMPOSITIONS AND METHODS FOR KILLING INSECT AND NON-INSECT PESTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2019-07-25 | — | — | WO | disclosed |
| US-20190216084-A1 | Compositions And Methods For Killing Insect And Non-Insect Pests | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2019-07-18 | — | — | US | disclosed |
| WO-2018138591-A1 | CALICHEAMICIN DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER INC. (US) | 2018-08-02 | — | — | WO | disclosed |
| CN-102066327-A | Iminopyridine derivatives and use thereof | TAKEDA PHARMACEUTICAL | 2011-05-18 | — | — | CN | disclosed |
| CN-101817770-A | Method for preparing methylthio-benzoic acid | UNIV JIANGSU POLYTECHNIC | 2010-09-01 | — | — | CN | disclosed |
| CN-101712641-A | Method for preparing methylthio benzoic acid | UNIV JIANGSU POLYTECHNIC | 2010-05-26 | — | — | CN | disclosed |
| CN-1554750-A | Subtilase variants and compositions | ŵά�Ź�˾ | 2004-12-15 | — | — | CN | disclosed |
| CN-1391473-A | VLA-4 inhibitor compounds | DAIICHI SEIYAKU CO (JP) | 2003-01-15 | — | — | CN | disclosed |
| CN-1298404-A | Inhibitors of phospholipase A2 | GENETICS INST (US) | 2001-06-06 | — | — | CN | disclosed |
| US-5750549-A | ANTIINFLAMMATORY AGENTS OR ANALGESICS | MERCK & CO., INC. (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1994011378-A1 | ARYL THIOPYRANO[2,3,4-c,d]INDOLES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1994-05-26 | — | — | WO | disclosed |
| US-5314900-A | Aryl thiopyrano[2,3,4-C,D]indoles as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA, INC. (CA) | 1994-05-24 | — | — | US | disclosed |
| US-3943153-A | BACTERICIDES | MERCK & CO., INC. (US) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230371508-A1 | COMPOSITIONS AND METHODS FOR KILLING INSECT AND NON-INSECT PESTS | BRS3, L3MBTL3, F7 | ALDH1A1 2593/4885KDM4E 89/4885MAPT 4316/4885 |
| US-11805776-B2 | Compositions and methods for killing insect and non-insect pests | BRS3, L3MBTL3, F7 | ALDH1A1 2593/4885KDM4E 89/4885MAPT 4316/4885 |
| US-20190216084-A1 | Compositions And Methods For Killing Insect And Non-Insect Pests | BRS3, L3MBTL3, F7 | ALDH1A1 2593/4885KDM4E 89/4885MAPT 4316/4885 |
| US-20220183287-A1 | METHODS FOR KILLING PESTS | L3MBTL3, AOC3, L3MBTL4 | ALDH1A1 884/4885KDM4E 566/4885MAPT 4242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.