Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 15/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.47 |
| ▸ | TACR2 | P21452 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799113 | 0.91 | LMNA (0.51) | TP53ALDH1A1LMNAGAAHRH1 | |
| SCHEMBL10549456 | 0.82 | HRH1 (0.49) | TP53LMNAGAAHRH1CYP2D6 | |
| SCHEMBL9536666 | 0.82 | HRH1 (0.49) | TP53LMNAGAAHRH1CYP2D6 | |
| SCHEMBL10798652 | 0.82 | HRH1 (0.49) | TP53LMNAGAAHRH1CYP2D6 | |
| SCHEMBL9535563 | 0.78 | TP53 (0.51) | TP53ALDH1A1LMNAGAAHRH1 | |
| Hydrochloric Acid SCHEMBL9537102 | 0.77 | HRH1 (0.56) | TP53HRH1CYP2D6KCNH2CHRM1 | |
| Hydrochloric Acid SCHEMBL10549097 | 0.77 | HRH1 (0.56) | TP53HRH1CYP2D6KCNH2CHRM1 | |
| Hydrochloric Acid SCHEMBL9537106 | 0.77 | HRH1 (0.56) | TP53HRH1CYP2D6KCNH2CHRM1 | |
| SCHEMBL9536973 | 0.77 | EED (0.47) | TP53LMNAGAAHRH1CYP2D6 | |
| SCHEMBL10549784 | 0.77 | EED (0.47) | TP53LMNAGAAHRH1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839374-A | TREATING ALLERGIES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1989-06-13 | — | — | US | disclosed |