Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237972 | 0.80 | ENPP2 (0.63) | ENPP2MMP3MEN1KMT2AKDM4E | |
| Benzene SCHEMBL5438521 | 0.78 | ENPP2 (0.61) | ENPP2MMP3MEN1KMT2AKDM4E | |
| SCHEMBL8249498 | 0.76 | TP53 (0.39) | KMT2ALMNAHTTCYP1A2HTR3E | |
| SCHEMBL694422 | 0.75 | ENPP2 (0.50) | ENPP2MMP3MEN1KMT2AKDM4E | |
| 1,1-Dichloroethene SCHEMBL9115415 | 0.75 | ENPP2 (0.44) | ENPP2MMP3MEN1KMT2AKDM4E | |
| SCHEMBL4374157 | 0.75 | ENPP2 (0.58) | ENPP2MMP3MEN1KMT2AKDM4E | |
| SCHEMBL6753195 | 0.75 | ENPP2 (0.53) | ENPP2MMP3MEN1KMT2AKDM4E | |
| SCHEMBL10549659 | 0.73 | HTR3E (0.36) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8255911 | 0.72 | CTBP2 (0.49) | NPC1 | |
| SCHEMBL11459736 | 0.71 | ENPP2 (0.50) | ENPP2MMP3KMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4827051-A | INSECTICIDE INTERMEDIATE | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1989-05-02 | — | — | US | disclosed |
| US-4668702-A | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-05-26 | — | — | US | disclosed |