Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152913 | 0.79 | HTR3E (0.32) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8255911 | 0.78 | CTBP2 (0.49) | CTBP2 | |
| SCHEMBL8249498 | 0.78 | TP53 (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL21597977 | 0.77 | HTR3E (0.33) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3365644 | 0.75 | AKR1B1 (0.58) | — | |
| SCHEMBL3113565 | 0.75 | CES1 (0.50) | CTBP2EPHX2 | |
| SCHEMBL8252472 | 0.73 | CTBP2 (0.53) | CTBP2 | |
| SCHEMBL10548906 | 0.73 | ENPP2 (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1355134 | 0.73 | — | — | |
| SCHEMBL10546280 | 0.73 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4827051-A | INSECTICIDE INTERMEDIATE | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1989-05-02 | — | — | US | disclosed |
| US-4668702-A | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-05-26 | — | — | US | disclosed |