Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PRNP | P04156 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391444 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL25746272 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL17904025 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAHPGDELANE | |
| SCHEMBL28229720 | 0.79 | KDM4E (0.55) | ALDH1A1KDM4EGAAHPGDELANE | |
| SCHEMBL9173175 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAAHPGDELANE | |
| SCHEMBL31391515 | 0.77 | POLB (0.43) | ALDH1A1KDM4EGAAHPGDMAPK1 | |
| SCHEMBL25746301 | 0.77 | POLB (0.43) | ALDH1A1KDM4EGAAHPGDMAPK1 | |
| SCHEMBL12409984 | 0.76 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EGAAHPGDELANE | |
| SCHEMBL10549627 | 0.76 | KMT2A (0.67) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL27912721 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAHPGDELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4855420-A | Cephalosporin derivatives | ICI PHARMA (FR) | 1989-08-08 | — | — | US | disclosed |
| US-4678781-A | BACTERICIDAL ANTIBIOTICS | ICI PHARMA (FR) | 1987-07-07 | — | — | US | disclosed |