Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391515 | 1.00 | POLB (0.43) | POLBNCF1PRNPRXFP1MAPK1 | |
| SCHEMBL25746272 | 0.80 | ALDH1A1 (0.47) | POLBPRNPRXFP1L3MBTL1MEN1 | |
| SCHEMBL31391444 | 0.80 | ALDH1A1 (0.47) | POLBPRNPRXFP1L3MBTL1MEN1 | |
| SCHEMBL26314584 | 0.78 | ADORA2A (0.50) | MAPK1L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL10548915 | 0.77 | ALDH1A1 (0.55) | POLBPRNPRXFP1MAPK1L3MBTL1 | |
| SCHEMBL6916233 | 0.72 | TDP1 (0.38) | L3MBTL1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL9433474 | 0.72 | KDM4E (0.57) | POLBNCF1L3MBTL1KMT2AKDM4E | |
| SCHEMBL9357207 | 0.70 | LMNA (0.52) | POLBNCF1PRNPRXFP1L3MBTL1 | |
| SCHEMBL31391505 | 0.70 | LMNA (0.52) | POLBNCF1PRNPRXFP1L3MBTL1 | |
| SCHEMBL30824487 | 0.68 | TSHR (0.41) | L3MBTL1KDM4EGPR3CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118507-A2 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2023-06-29 | — | — | WO | disclosed |