Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PRNP | P04156 | 6/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391444 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAPRNPNPSR1 | |
| SCHEMBL10548915 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAPRNPNPSR1 | |
| SCHEMBL31391515 | 0.80 | POLB (0.43) | ALDH1A1KDM4ELMNAPRNPNPSR1 | |
| SCHEMBL25746301 | 0.80 | POLB (0.43) | ALDH1A1KDM4ELMNAPRNPNPSR1 | |
| SCHEMBL10171939 | 0.78 | POLB (0.54) | ALDH1A1KDM4ELMNAPRNPNPSR1 | |
| SCHEMBL14985883 | 0.78 | GPR3 (0.55) | ALDH1A1KDM4ELMNAPRNPNPSR1 | |
| SCHEMBL24015454 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAPRNPNPSR1 | |
| SCHEMBL859288 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAPRNPNPSR1 | |
| Ammonia Solution, Strong SCHEMBL28418689 | 0.77 | POLB (0.53) | ALDH1A1KDM4ELMNAPRNPNPSR1 | |
| SCHEMBL29109414 | 0.77 | DCPS (0.57) | ALDH1A1KDM4ELMNAPRNPNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118507-A2 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2023-06-29 | — | — | WO | disclosed |