Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | CASR | P41180 | 2/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321763 | 0.82 | CYP19A1 (0.50) | IDO1MAPT | |
| SCHEMBL4275946 | 0.81 | TAAR1 (0.49) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4274050 | 0.80 | TAAR1 (0.48) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1229637 | 0.79 | LOXL2 (0.60) | LOXL2IDO1OPRK1CASRMTNR1A | |
| SCHEMBL24027062 | 0.78 | LOXL2 (0.63) | LOXL2IDO1OPRK1CASRKDM4E | |
| SCHEMBL1460651 | 0.78 | LOXL2 (0.58) | LOXL2IDO1OPRK1CASRMTNR1A | |
| SCHEMBL8292122 | 0.78 | GAA (0.48) | LOXL2KDM4EALDH1A1GAAMAPT | |
| SCHEMBL4104078 | 0.77 | OPRK1 (0.73) | LOXL2IDO1OPRK1 | |
| SCHEMBL3740363 | 0.77 | MTNR1A (0.48) | IDO1CASRNLRP3KDM4EALDH1A1 | |
| SCHEMBL3560619 | 0.76 | IDO1 (0.58) | LOXL2IDO1OPRK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108892634-B | Indolylmethylaniline compound and application thereof | 浙江工业大学 | 2021-04-23 | — | — | CN | claimed |
| CN-108892634-B | Indolylmethylaniline compound and application thereof | 浙江工业大学 | 2021-04-23 | — | — | CN | disclosed |
| CN-108892634-B | Indolylmethylaniline compound and application thereof | 浙江工业大学 | 2021-04-23 | — | — | CN | disclosed |
| CN-108892634-B | Indolylmethylaniline compound and application thereof | 浙江工业大学 | 2021-04-23 | — | — | CN | disclosed |
| US-4839369-A | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | RORER PHARMACEUTICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |
| US-4728668-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORPORATION (US) | 1988-03-01 | — | — | US | disclosed |
| US-4725619-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORPORATION (US) | 1988-02-16 | — | — | US | disclosed |
| US-4631287-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORP. (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0200101-A2 | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive aliments | USV PHARMACEUTICAL CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |