Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222919 | 0.83 | MEN1 (0.43) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL15093959 | 0.83 | MEN1 (0.43) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL15093765 | 0.83 | MEN1 (0.43) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL5864259 | 0.81 | MCHR1 (0.55) | NPC1RAB9ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13169522 | 0.80 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL217929 | 0.79 | TNK2 (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL1186911 | 0.79 | MEN1 (0.52) | NPC1RAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL10499836 | 0.79 | EPHX2 (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL15214979 | 0.78 | ALDH1A1 (0.41) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7155013 | 0.78 | ALDH1A1 (0.41) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824993-A | SYNTHETIC PROSTAGLANDINS, ANTISECRETORY AGENTS | GLAXO GROUP LIMITED (GB) | 1989-04-25 | — | — | US | disclosed |