Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PCNA | P12004 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15214980 | 1.00 | ALDH1A1 (0.41) | ALDH1A1HSD11B1MEN1KMT2AESR1 | |
| SCHEMBL15214979 | 1.00 | ALDH1A1 (0.41) | ALDH1A1HSD11B1MEN1KMT2AESR1 | |
| SCHEMBL15093959 | 0.95 | MEN1 (0.43) | ALDH1A1HSD11B1MEN1KMT2AESR1 | |
| SCHEMBL222919 | 0.95 | MEN1 (0.43) | ALDH1A1HSD11B1MEN1KMT2AESR1 | |
| SCHEMBL15093765 | 0.95 | MEN1 (0.43) | ALDH1A1HSD11B1MEN1KMT2AESR1 | |
| SCHEMBL217929 | 0.90 | TNK2 (0.43) | ALDH1A1HSD11B1MEN1KMT2AESR1 | |
| SCHEMBL15049914 | 0.89 | HPGD (0.47) | ALDH1A1HSD11B1MEN1KMT2AESR1 | |
| SCHEMBL16055037 | 0.87 | HSD11B1 (0.41) | ALDH1A1HSD11B1MEN1KMT2AHPGD | |
| SCHEMBL21400657 | 0.86 | APP (0.44) | HSD11B1MEN1KMT2ATNK2PTPN1 | |
| SCHEMBL30279565 | 0.85 | CALM1 (0.41) | HSD11B1MEN1KMT2AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748307-B1 | SKIN LIGHTENING COMPOSITIONS | PROCTER & GAMBLE (US) | 2001-12-12 | — | — | EP | claimed |
| US-6068834-A | ORALLY ADMINISTERING A MELANINS REDUCING OXY PHENOL COMPOUND TO THE MAMMAL FOR LIGHTENING THE MAMMALIAN SKIN; TYROSINASE INHIBITOR | THE PROCTER & GAMBLE COMPANY (US) | 2000-05-30 | — | — | US | claimed |
| EP-0748307-A1 | SKIN LIGHTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-18 | — | — | EP | claimed |
| WO-1995023780-A2 | SKIN LIGHTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1995-09-08 | — | — | WO | claimed |
| US-20130224137-A1 | SKIN LIGHTENING COMPOSITIONS | LASYA, INC. (US) | 2013-08-29 | — | — | US | disclosed |
| US-6537527-B1 | Such as 2-fluoro-4-((tetrahydro-2H-pyran-2-yl)oxy)phenol and carrier; efficient; nonirritating; resistant to oxidation from light, air, and tyrosinase | CHILDREN'S HOSPITAL MEDICAL CENTER | 2003-03-25 | — | — | US | disclosed |
| EP-0748307-B1 | SKIN LIGHTENING COMPOSITIONS | PROCTER & GAMBLE (US) | 2001-12-12 | — | — | EP | disclosed |
| US-6068834-A | ORALLY ADMINISTERING A MELANINS REDUCING OXY PHENOL COMPOUND TO THE MAMMAL FOR LIGHTENING THE MAMMALIAN SKIN; TYROSINASE INHIBITOR | THE PROCTER & GAMBLE COMPANY (US) | 2000-05-30 | — | — | US | disclosed |
| US-5932196-A | DEOXYARBUTIN DERIVATIVES, STORAGE STABILITY | THE PROCTER & GAMBLE COMPANY (US) | 1999-08-03 | — | — | US | disclosed |
| US-5811593-A | MADE BY REACTING HYDROQUINONE MONOETHER WITH ENOL ETHER IN PRESENCE OF ACID CATALYST, REACTING PRODUCT WITH HYDROGEN TRANSFER AGENT IN PRESENCE OF METAL CATALYST TO CLEAVE PROTECTING GROUP | THE PROCTER & GAMBLE COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| EP-0748306-A1 | PROCESS FOR MAKING MONOACETALS OF HYDROQUINONE | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-18 | — | — | EP | disclosed |
| EP-0748307-A1 | SKIN LIGHTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-18 | — | — | EP | disclosed |
| US-5585525-A | Process for making monoacetals of hydroquinone | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-17 | — | — | US | disclosed |
| WO-1995023780-A2 | SKIN LIGHTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |
| WO-1995023779-A2 | PROCESS FOR MAKING MONOACETALS OF HYDROQUINONE | THE PROCTER & GAMBLE COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |
| WO-1995023778-A2 | PROCESS FOR MAKING MONOACETALS OF HYDROQUINONE | THE PROCTER & GAMBLE COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130224137-A1 | SKIN LIGHTENING COMPOSITIONS | CUTA, COL14A1, COLGALT1 | ALDH1A1 500/4885HSD11B1 1544/4885MEN1 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.