Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 3/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10594469 | 0.79 | CTSB (0.38) | CYP4F2CYP4A11CTSBCTSSCTSL | |
| SCHEMBL500447 | 0.78 | SPHK1 (0.49) | CYP4F2CYP4A11CTSBCTSSCTSL | |
| SCHEMBL13502694 | 0.77 | CTSB (0.36) | CYP4F2CYP4A11CTSBCTSSCTSL | |
| SCHEMBL9671904 | 0.77 | SPHK1 (0.48) | CYP4F2CYP4A11CTSBCTSSCTSL | |
| SCHEMBL4764313 | 0.77 | CNR2 (0.42) | CYP4F2CYP4A11CTSBCTSSCTSL | |
| SCHEMBL8485391 | 0.76 | CNR2 (0.39) | CYP4F2CYP4A11CTSBCTSSCTSL | |
| SCHEMBL8683974 | 0.74 | CYP2C19 (0.36) | CYP4F2CYP4A11CTSBCTSSCTSL | |
| SCHEMBL14088075 | 0.74 | CYP1A2 (0.38) | CYP4F2CYP4A11CTSBCTSSCTSL | |
| SCHEMBL7439122 | 0.74 | CTSB (0.46) | CYP4F2CYP4A11CTSBCTSSCTSL | |
| SCHEMBL4317114 | 0.74 | CTSL (0.63) | CTSBCTSLALDH1A1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833152-A | Anti-hypertensive agents | UNIVERSITY OF MIAMI (US) | 1989-05-23 | — | — | US | disclosed |
| US-4745124-A | THIO/ESTER PEPTIDES | UNIVERSITY OF MIAMI (US) | 1988-05-17 | — | — | US | disclosed |
| US-4734420-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | UNIVERSITY OF MIAMI (US) | 1988-03-29 | — | — | US | disclosed |
| US-4692458-A | Anti-hypertensive agents | UNIVERSITY OF MIAMI (US) | 1987-09-08 | — | — | US | disclosed |
| US-4690936-A | AMINO ACIDS, THIOESTER LINKAGE; ANGIOTENSIN INHIBITORS | UNIVERSITY OF MIAMI (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0036713-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | UNIVERSITY OF MIAMI (US) | 1984-01-18 | — | — | EP | disclosed |
| EP-0036713-A2 | Angiotensin converting enzyme inhibitors | UNIVERSITY OF MIAMI (US) | 1981-09-30 | — | — | EP | disclosed |
| US-4108886-A | Thiopropanoylamino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1978-08-22 | — | — | US | disclosed |