Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671904 | 0.98 | SPHK1 (0.48) | SPHK1EPHX2CNR2CYP4F2CYP4A11 | |
| SCHEMBL15297852 | 0.86 | SPHK1 (0.65) | SPHK1EPHX2MEN1KMT2AFAAH | |
| SCHEMBL15297190 | 0.86 | SPHK1 (0.65) | SPHK1EPHX2MEN1KMT2AFAAH | |
| SCHEMBL15285134 | 0.86 | SPHK1 (0.65) | SPHK1EPHX2MEN1KMT2AFAAH | |
| SCHEMBL1131711 | 0.84 | SPHK1 (0.55) | SPHK1EPHX2MEN1KMT2AFAAH | |
| SCHEMBL8485391 | 0.81 | CNR2 (0.39) | CNR2CYP4F2CYP4A11CTSBCTSS | |
| SCHEMBL6840056 | 0.80 | SPHK1 (0.44) | SPHK1EPHX2MEN1KMT2AFAAH | |
| SCHEMBL27760068 | 0.78 | SPHK1 (0.52) | SPHK1EPHX2CNR2MEN1KMT2A | |
| SCHEMBL29242051 | 0.78 | EPHX2 (0.45) | SPHK1EPHX2CNR2MEN1KMT2A | |
| SCHEMBL13146756 | 0.78 | EPHX2 (0.45) | SPHK1EPHX2MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113933414-B | Method for detecting organic impurities in amlodipine besylate composite preparation | 株洲千金药业股份有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-113933414-A | Method for detecting organic impurities in irbesartan amlodipine besylate composite preparation | 株洲千金药业股份有限公司 | 2022-01-14 | — | — | CN | claimed |
| US-8106216-B2 | Process for the preparation of Irbesartan | AUROBINDO PHARMA LTD. (IN) | 2012-01-31 | — | — | US | claimed |
| US-20100056797-A1 | Process for the Preparation of Irbesartan | AUROBINDO PHARMA LTD (IN) | 2010-03-04 | — | — | US | claimed |
| WO-2007122508-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF IRBESARTAN | AUROBINDO PHARMA LIMITED (IN) | 2007-11-01 | — | — | WO | claimed |
| CN-118852127-B | Method for removing impurities in irbesartan | 浙江弘盛药业有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-118852127-A | Method for removing impurities in irbesartan | 浙江弘盛药业有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-113933414-B | Method for detecting organic impurities in amlodipine besylate composite preparation | 株洲千金药业股份有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-113933414-A | Method for detecting organic impurities in irbesartan amlodipine besylate composite preparation | 株洲千金药业股份有限公司 | 2022-01-14 | — | — | CN | disclosed |
| US-8106216-B2 | Process for the preparation of Irbesartan | AUROBINDO PHARMA LTD. (IN) | 2012-01-31 | — | — | US | disclosed |
| US-8106216-B2 | Process for the preparation of Irbesartan | AUROBINDO PHARMA LTD. (IN) | 2012-01-31 | — | — | US | disclosed |
| WO-2010079405-A3 | AN IMPROVED PROCESS FOR PREPARING 1-(PENTANOYLAMINO)CYCLOPENTANECARBOXYLIC ACID | ALEMBIC LIMITED (IN) | 2011-10-06 | — | — | WO | disclosed |
| WO-2007049293-A1 | AN IMPROVED PROCESS FOR PREPARATION OF IRBESARTAN | ALEMBIC LIMITED (IN) | 2007-05-03 | — | — | WO | disclosed |
| WO-2007049293-A1 | AN IMPROVED PROCESS FOR PREPARATION OF IRBESARTAN | ALEMBIC LIMITED (IN) | 2007-05-03 | — | — | WO | disclosed |
| EP-1751123-A1 | PROCESS FOR PREPARING IRBESARTAN | Dr. Reddy's Laboratories Ltd. (IN) | 2007-02-14 | — | — | EP | disclosed |
| EP-1751123-A1 | PROCESS FOR PREPARING IRBESARTAN | Dr. Reddy's Laboratories Ltd. (IN) | 2007-02-14 | — | — | EP | disclosed |
| WO-2006089927-A1 | METHOD FOR OBTAINING A PHARMACEUTICALLY ACTIVE COMPOUND (IRBESARTAN) AND ITS SYNTHESIS INTERMEDIATE | INKE, S.A. (ES) | 2006-08-31 | — | — | WO | disclosed |
| WO-2005113518-A1 | PROCESS FOR PREPARING IRBESARTAN | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-12-01 | — | — | WO | disclosed |
| WO-2005113518-A1 | PROCESS FOR PREPARING IRBESARTAN | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-12-01 | — | — | WO | disclosed |
| EP-0475898-A1 | Azacyclic compounds | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056797-A1 | Process for the Preparation of Irbesartan | AGTR1, REN, AGTR2 | SPHK1 1145/4885EPHX2 2339/4885CNR2 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.