Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537082 | 0.87 | HTR2A (0.56) | HRH1MEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL10549103 | 0.86 | SLC18A2 (0.53) | ACHEHRH1MEN1ALDH1A1LMNA | |
| SCHEMBL9740363 | 0.86 | SSTR5 (0.66) | HRH1MEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL9536214 | 0.85 | SLC18A2 (0.53) | ACHEHRH1MEN1ALDH1A1LMNA | |
| SCHEMBL10551946 | 0.85 | TSHR (0.52) | ACHEHRH1MEN1ALDH1A1LMNA | |
| SCHEMBL10552682 | 0.82 | USP2 (0.47) | HRH1MEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL10546931 | 0.82 | GRIN1 (0.47) | HRH1MEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL9539669 | 0.81 | RAB9A (0.52) | HRH1MEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL10550542 | 0.81 | SLC18A2 (0.55) | ACHEHRH1MEN1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL10550967 | 0.80 | NOS2 (0.42) | HRH1KCNH2SSTR5HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839374-A | TREATING ALLERGIES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1989-06-13 | — | — | US | disclosed |
| US-4695575-A | ANTIHISTAMINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1987-09-22 | — | — | US | disclosed |