SCHEMBL10550352

SCHEMBL10550352

CNC(=O)Oc1ncccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
ACHE P22303 2/20 0.42
PGR P06401 1/20 0.42
GAA P10253 1/20 0.42
PTGS1 P23219 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
POLB P06746 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PLK1 P53350 1/20 0.35
BCHE P06276 1/20 0.35
P2RX7 Q99572 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10552758 0.81 ALDH1A1 (0.38) ALDH1A1ACHEPGRGAAPTGS1
SCHEMBL7603398 0.78 KMT2A (0.45) GAAMEN1KMT2APOLBLMNA
SCHEMBL21550861 0.78 ALDH1A1 (0.36) ALDH1A1ACHEPGRGAAPTGS1
SCHEMBL29100881 0.78 TSHR (0.41) ALDH1A1GAAHSD17B10POLBLMNA
SCHEMBL29141779 0.77 ALDH1A1 (0.43) ALDH1A1ACHEPGRGAAPTGS1
SCHEMBL12052657 0.76 ALDH1A1 (0.49) ALDH1A1ACHEPGRGAAPTGS1
SCHEMBL1291212 0.75 KDM4E (0.43) ALDH1A1PTGS1HSD17B10MEN1KMT2A
SCHEMBL1161075 0.74 KMT2A (0.37) ALDH1A1GAAMEN1KMT2ATDP1
SCHEMBL29136750 0.74 ALDH1A1 (0.47) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL4536928 0.73 P2RX7 (0.41) ALDH1A1GAAMEN1KMT2AP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0085476-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-22 EP claimed
EP-0085476-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-08-10 EP claimed
CN-112368289-B C26-linked rapamycin analogues as MTOR inhibitors 锐新医药公司 2024-02-20 CN disclosed
US-4878938-A PRE- AND POSTEMERGENCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-11-07 US disclosed
US-4810282-A 3-ORTHO-(ISOXAZOLYL,ISOTHIAZOLYL, PYRAZOLYL,THIADIAZOLYL, OXADIAZOLYL AND TRIAZOLYL BENZENESULFONUREYLENE-1,2,4-TRIAZOLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-03-07 US disclosed
US-4776878-A PLANT GROWTH REGULATORS OR HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-10-11 US disclosed
US-4770690-A Herbicidal ortho-alkyl- and ortho-alkenyl-substituted benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-13 US disclosed
US-4767445-A Herbicidal ortho-(azinyl)-benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-08-30 US disclosed
US-4764204-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-08-16 US disclosed
EP-0106512-B1 HERBICIDAL ORTHO-ALKYL- AND ORTHO-ALKENYL-SUBSTITUTED BENZENESULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-18 EP disclosed
EP-0083975-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-19 EP disclosed
US-4435206-A PREEMERGENCE AND POSTEMERGENCE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-06 US disclosed
US-4424377-A HERBICIDES E. I. DU PONT DE NEMOURS & CO. (US) 1984-01-03 US disclosed
EP-0094790-A2 Herbicidal O-alkoxybenzenesulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-11-23 EP disclosed
EP-0085476-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-08-10 EP disclosed
EP-0083975-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-20 EP disclosed
EP-0079683-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-05-25 EP disclosed
US-4369320-A PLANT GROWTH RETARDERS, HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-18 US disclosed
US-4348220-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-07 US disclosed
EP-0051465-A1 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-05-12 EP disclosed