SCHEMBL10550357

SCHEMBL10550357

COC(=O)Nc1ncccn1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
KDM4E B2RXH2 2/20 0.54
KMT2A Q03164 1/20 0.54
LMNA P02545 1/20 0.53
HTT P42858 1/20 0.53
NPSR1 Q6W5P4 2/20 0.46
GAA P10253 1/20 0.46
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
GLA P06280 1/20 0.44
TDP1 Q9NUW8 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28037824 0.80 RAB9A (0.47) ALDH1A1KDM4ELMNAHTTNPSR1
SCHEMBL3368297 0.80 EPHX2 (0.41) ALDH1A1KDM4EKMT2ALMNAHTT
SCHEMBL1029793 0.79 KDM4E (0.49) ALDH1A1KDM4ELMNAHTTGAA
SCHEMBL8241210 0.78 HPGD (0.46) ALDH1A1KDM4EKMT2ALMNAHTT
SCHEMBL17578455 0.78 SMN1; SMN2 (0.39) ALDH1A1KDM4EKMT2ALMNAGAA
SCHEMBL27838989 0.77 SCN9A (0.44) ALDH1A1KDM4EKMT2ANPC1RAB9A
SCHEMBL29141778 0.77 NPC1 (0.55) ALDH1A1KDM4EKMT2ANPSR1GAA
SCHEMBL21508445 0.77 KDM4E (0.43) ALDH1A1KDM4EKMT2ANPC1RAB9A
SCHEMBL2491687 0.76 LMNA (0.63) ALDH1A1KDM4EKMT2ALMNAHTT
SCHEMBL23566413 0.75 LMNA (0.56) ALDH1A1KDM4EKMT2ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0085476-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-22 EP claimed
EP-0085476-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-08-10 EP claimed
US-4878938-A PRE- AND POSTEMERGENCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-11-07 US disclosed
US-4810282-A 3-ORTHO-(ISOXAZOLYL,ISOTHIAZOLYL, PYRAZOLYL,THIADIAZOLYL, OXADIAZOLYL AND TRIAZOLYL BENZENESULFONUREYLENE-1,2,4-TRIAZOLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-03-07 US disclosed
US-4776878-A PLANT GROWTH REGULATORS OR HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-10-11 US disclosed
US-4770690-A Herbicidal ortho-alkyl- and ortho-alkenyl-substituted benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-13 US disclosed
US-4767445-A Herbicidal ortho-(azinyl)-benzenesulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-08-30 US disclosed
US-4764204-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-08-16 US disclosed
EP-0106512-B1 HERBICIDAL ORTHO-ALKYL- AND ORTHO-ALKENYL-SUBSTITUTED BENZENESULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-18 EP disclosed
EP-0083975-B1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-19 EP disclosed
US-4705556-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-10 US disclosed
US-4435206-A PREEMERGENCE AND POSTEMERGENCE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-06 US disclosed
US-4424377-A HERBICIDES E. I. DU PONT DE NEMOURS & CO. (US) 1984-01-03 US disclosed
EP-0094790-A2 Herbicidal O-alkoxybenzenesulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-11-23 EP disclosed
EP-0085476-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-08-10 EP disclosed
EP-0083975-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-20 EP disclosed
EP-0079683-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-05-25 EP disclosed
US-4369320-A PLANT GROWTH RETARDERS, HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-18 US disclosed
US-4348220-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-07 US disclosed
EP-0051465-A1 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-05-12 EP disclosed