SCHEMBL2491687

SCHEMBL2491687

CC(=O)Nc1ncccn1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.63
HTT P42858 1/20 0.63
L3MBTL1 Q9Y468 2/20 0.51
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
ADORA1 P30542 1/20 0.46
CYP1A2 P05177 1/20 0.45
NAPRT Q6XQN6 1/20 0.44
HSD17B10 Q99714 1/20 0.44
GAA P10253 1/20 0.44
POLB P06746 1/20 0.43
FFAR2 O15552 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholine SCHEMBL28179787 0.80 LMNA (0.45) LMNAHTTL3MBTL1KDM4EMEN1
SCHEMBL23566413 0.79 LMNA (0.56) LMNAHTTKDM4EMEN1KMT2A
SCHEMBL13204664 0.79 RAB9A (0.58) LMNAHTTKMT2AALDH1A1
SCHEMBL9948710 0.78 L3MBTL1 (0.50) LMNAHTTL3MBTL1KDM4EMEN1
SCHEMBL8079170 0.78 HTT (0.55) LMNAHTTL3MBTL1KDM4EKMT2A
SCHEMBL19308408 0.78 LMNA (1.00) LMNAHTTL3MBTL1KDM4EMEN1
SCHEMBL4303429 0.77 LMNA (0.54) LMNAHTTKDM4EKMT2AALDH1A1
SCHEMBL30142804 0.76 POLB (0.54) LMNAMEN1KMT2AALDH1A1POLB
SCHEMBL24073678 0.76 POLB (0.54) LMNAMEN1KMT2AALDH1A1POLB
SCHEMBL10550357 0.76 ALDH1A1 (0.54) LMNAHTTKDM4EKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016124553-A1 2-PHENYL-3H-IMIDAZO[4,5-B]PYRIDINE DERIVATES USEFUL AS INHIBITORS OF MAMMALIAN TYROSINE KINASE ROR1 ACTIVITY KANCERA AB (SE) 2016-08-11 WO claimed
CN-102690607-B Metal polishing slurry and application thereof HITACHI CHEMICAL CO LTD 2015-02-11 CN claimed
EP-0151826-B1 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines JANSSEN PHARMACEUTICA N.V. (BE) 1993-03-31 EP claimed
US-20260146199-A1 METHOD FOR PROCESSING SEMICONDUCTOR SUBSTRATE, METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE, AND PROCESSING SOLUTION FOR SEMICONDUCTOR DEVICE TOKYO OHKA KOGYO CO., LTD. (JP) 2026-05-28 US disclosed
US-12630742-B2 Polishing composition using polishing particles containing basic substance and having high water affinity NISSAN CHEMICAL CORPORATION (JP) 2026-05-19 US disclosed
US-20260117105-A1 POLISHING COMPOSITION HAVING EXCELLENT STORAGE STABILITY AND METHOD FOR PRODUCING SAME NISSAN CHEMICAL CORPORATION (JP) 2026-04-30 US disclosed
US-20260042978-A1 PROCESSING SOLUTION FOR SEMICONDUCTOR DEVICE TOKYO OHKA KOGYO CO LTD (JP) 2026-02-12 US disclosed
US-20260028553-A1 PROCESSING SOLUTION, METHOD FOR MANUFACTURING PROCESSING SOLUTION, METHOD FOR PROCESSING SUBSTRATE, AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE TOKYO OHKA KOGYO CO LTD (JP) 2026-01-29 US disclosed
US-20260008780-A1 SUBSTITUTED 3,4-DIHYDROISOQUINOLIN-1(2H)-ONE DERIVATIVES AND RELATED USES NODTHERA LTD (GB) 2026-01-08 US disclosed
US-12516420-B2 Chemical solution for removing precious metal, method for manufacturing chemical solution, method for treating substrate, method for manufacturing semiconductor device TOKYO OHKA KOGYO CO., LTD. (JP) 2026-01-06 US disclosed
US-12480077-B2 Aqueous cleaning liquid and method of cleaning electronic device TOKYO OHKA KOGYO CO., LTD. (JP) 2025-11-25 US disclosed
US-7160877-B2 Aliphatic nitrogen-containing 5-membered ring compound TANABE SEIYAKU CO., LTD. (JP) 2007-01-09 US disclosed
CN-1845907-A Guanidine derivatives ACTELION PHARMACEUTICALS LTD (CH) 2006-10-11 CN disclosed
WO-2005123955-A2 METHODS AND COMPOSITIONS FOR MODIFYING GENE REGULATION AND DNA DAMAGE IN AGEING CHILDREN'S MEDICAL CENTER CORPORATION (US) 2005-12-29 WO disclosed
CN-1659688-A Polishing liquid and polishing method HITACHI CHEMICAL CO LTD (JP) 2005-08-24 CN disclosed
US-20050181609-A1 Polishing fluid and polishing method HITACHI CHEMICAL CO., LTD. (JP) 2005-08-18 US disclosed
CN-1650403-A Polishing liquid and polishing method HITACHI CHEMICAL CO LTD (JP) 2005-08-03 CN disclosed
EP-1505639-A1 POLISHING FLUID AND POLISHING METHOD HITACHI CHEMICAL COMPANY, LTD. (JP) 2005-02-09 EP disclosed
WO-1998017684-A2 DNA SEQUENCES ENCODING FUSIONS OF DNA REPAIR PROTEINS AND USES THEREOF ADVANCED RESEARCH & TECHNOLOGY INSTITUTE (US) 1998-04-30 WO disclosed
EP-0151826-B1 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines JANSSEN PHARMACEUTICA N.V. (BE) 1993-03-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117105-A1 POLISHING COMPOSITION HAVING EXCELLENT STORAGE STABILITY AND METHOD FOR PRODUCING SAME SRPRA, SEM1, PSMA1 LMNA 1106/4885HTT 2397/4885L3MBTL1 3139/4885
US-20260028553-A1 PROCESSING SOLUTION, METHOD FOR MANUFACTURING PROCESSING SOLUTION, METHOD FOR PROCESSING SUBSTRATE, AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE TET2, TET1, KDM2A LMNA 3633/4885HTT 3865/4885L3MBTL1 3661/4885
US-20260042978-A1 PROCESSING SOLUTION FOR SEMICONDUCTOR DEVICE TWF2, DSTYK, WNK1 LMNA 4667/4885HTT 3321/4885L3MBTL1 3539/4885
US-20260146199-A1 METHOD FOR PROCESSING SEMICONDUCTOR SUBSTRATE, METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE, AND PROCESSING SOLUTION FOR SEMICONDUCTOR DEVICE AS3MT, ASH1L, HMOX2 LMNA 4210/4885HTT 509/4885L3MBTL1 3120/4885
US-12630742-B2 Polishing composition using polishing particles containing basic substance and having high water affinity POLR1A, PRMT1, SRRM2 LMNA 978/4885HTT 4033/4885L3MBTL1 4300/4885
US-20260008780-A1 SUBSTITUTED 3,4-DIHYDROISOQUINOLIN-1(2H)-ONE DERIVATIVES AND RELATED USES NOD1, NLRP3, CASP1 LMNA 650/4885HTT 3791/4885L3MBTL1 2066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.