Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687511 | 0.84 | DHFR (0.62) | DHFRHRH3KDM4EALDH1A1LMNA | |
| SCHEMBL10741158 | 0.84 | KDM4E (0.44) | DHFRHRH3KDM4EALDH1A1LMNA | |
| SCHEMBL10747566 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL10743308 | 0.81 | CSF1R (0.47) | HRH3KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10747557 | 0.79 | DPP4 (0.45) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL10501993 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL2617022 | 0.77 | CHRM2 (0.53) | KDM4EALDH1A1LMNADPP4KCNH2 | |
| SCHEMBL11713046 | 0.76 | TSHR (0.62) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL6820686 | 0.75 | DPP4 (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL11716334 | 0.74 | TSHR (0.43) | KDM4EALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4840954-A | BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | claimed |
| US-4840954-A | BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |