Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TOP2A | P11388 | 8/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 8/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7578567 | 0.87 | KDM4E (0.48) | DPP4KDM4ETOP2ATOP2BCHRM2 | |
| SCHEMBL10562097 | 0.84 | LMNA (0.61) | DPP4KDM4ETOP2ATOP2BLMNA | |
| SCHEMBL10994928 | 0.81 | DHFR (0.48) | DPP4KDM4ETOP2ATOP2BCHRM2 | |
| SCHEMBL10747566 | 0.80 | KDM4E (0.47) | DPP4KDM4ETOP2ATOP2BCHRM2 | |
| SCHEMBL10559283 | 0.80 | LMNA (0.58) | KDM4ETOP2ATOP2BLMNAABCC4 | |
| SCHEMBL10876232 | 0.79 | DPP4 (0.59) | DPP4KDM4ETOP2ATOP2BCHRM2 | |
| SCHEMBL2617022 | 0.78 | CHRM2 (0.53) | DPP4KDM4ETOP2ATOP2BCHRM2 | |
| SCHEMBL10743308 | 0.77 | CSF1R (0.47) | DPP4KDM4ETOP2ATOP2BCHRM2 | |
| SCHEMBL10501993 | 0.77 | KDM4E (0.54) | DPP4KDM4ETOP2ATOP2BCHRM2 | |
| SCHEMBL7960307 | 0.77 | KDM4E (0.55) | DPP4KDM4ETOP2ATOP2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763359-A1 | Pharmaceutical composition for topical use | R.R.A. S.r.l. (IT) | 1997-03-19 | — | — | EP | claimed |
| EP-0049355-B1 | 7-Amino-1-cyclopropyl-4-oxo-1,4-dihydro-(naphthyridine or quinoline)-3-carboxylic acids, process for their preparation and pharmaceutical compositions containing them | BAYER AG (DE) | 1984-10-10 | — | — | EP | claimed |
| US-20040082593-A1 | Infusion of ciprofloxacin having reduced acid content and being stable in storage | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-0763359-A1 | Pharmaceutical composition for topical use | R.R.A. S.r.l. (IT) | 1997-03-19 | — | — | EP | disclosed |
| EP-0763359-A1 | Pharmaceutical composition for topical use | R.R.A. S.r.l. (IT) | 1997-03-19 | — | — | EP | disclosed |
| US-5077429-A | 7-AMINO-1-CYCLOPROPYL-4-OXO-1,4-DIHYDRO-QUINOLINE- AND NAPHTHYRIDINE-3-CARBOXYLIC ACIDS, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS CONTAINING THESE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-31 | — | — | US | disclosed |
| EP-0153828-B1 | 1-CYCLOPROPYL-1, 4-DIHYDRO-6-FLUORO-4-OXO-1, 8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS; THEIR DERIVATIVES AND A PROCESS FOR PREPARING THE COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4762844-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| US-4670444-A | 7-amino-1-cyclopropyl-4-oxo-1, 4-dihydro-quinoline-and naphthyridine-3-carboxylic acids and antibacterial agents containing these compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1987-06-02 | — | — | US | disclosed |
| US-4620007-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-28 | — | — | US | disclosed |
| EP-0049355-A1 | 7-Amino-1-cyclopropyl-4-oxo-1,4-dihydro-(naphthyridine or quinoline)-3-carboxylic acids, process for their preparation and pharmaceutical compositions containing them | BAYER AG (DE) | 1982-04-14 | — | — | EP | disclosed |