Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 4/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 7/20 | 0.41 |
| ▸ | RARG | P13631 | 7/20 | 0.41 |
| ▸ | RXRA | P19793 | 5/20 | 0.41 |
| ▸ | RARA | P10276 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553327 | 0.87 | TNKS (0.57) | TNKSABCB1ABCC1RARBRARG | |
| SCHEMBL10550637 | 0.75 | TNKS (0.62) | TNKSKDM4ETP53HSD17B10HPGD | |
| SCHEMBL9833244 | 0.74 | MAOB (0.49) | TNKSABCB1KDM4ETP53HSD17B10 | |
| SCHEMBL9866561 | 0.73 | RARB (0.61) | ABCB1ABCC1RARBRARGRXRA | |
| SCHEMBL25201659 | 0.72 | KDM4E (0.73) | TNKSABCB1KDM4ETP53HSD17B10 | |
| SCHEMBL6292577 | 0.72 | RARB (0.51) | RARBRARGRXRARARAKDM4E | |
| SCHEMBL25204150 | 0.71 | KDM4E (0.73) | TNKSABCB1KDM4ETP53HSD17B10 | |
| SCHEMBL28043561 | 0.70 | CSNK2A2 (0.72) | TNKSABCB1ABCC1KDM4ETP53 | |
| SCHEMBL6423981 | 0.69 | RARB (0.68) | RARBRARGRXRARARA | |
| SCHEMBL8771700 | 0.69 | RXRA (0.67) | RARBRARGRXRARARARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831052-A | DIFFERENTIATION-INDUCING AGENT FOR CERTAIN MALIONANT CELLS | SHIONOGI & CO., LTD. (JP) | 1989-05-16 | — | — | US | claimed |