Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553327 | 0.87 | TNKS (0.57) | TNKSABCB1 | |
| SCHEMBL10550637 | 0.84 | TNKS (0.62) | MAOBTP53MAPTCYP3A4MEN1 | |
| SCHEMBL9836023 | 0.79 | MAPT (0.52) | TP53MAPTCYP3A4MEN1KMT2A | |
| SCHEMBL9359800 | 0.76 | RARB (0.52) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL25330135 | 0.75 | MAPT (0.66) | MAOBTP53MAPTCYP3A4MEN1 | |
| SCHEMBL10550483 | 0.74 | TNKS (0.51) | MAOBTP53MAPTCYP3A4KDM4E | |
| Acetic Acid SCHEMBL311830 | 0.72 | TNKS (0.67) | MAOBTP53MAPTCYP3A4MEN1 | |
| SCHEMBL21417969 | 0.72 | MAPT (0.78) | MAOBTP53MAPTCYP3A4MEN1 | |
| SCHEMBL311927 | 0.71 | TNKS (0.71) | MAOBTP53MAPTCYP3A4MEN1 | |
| SCHEMBL4172232 | 0.71 | MAPT (0.74) | MAOBTP53MAPTCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237986-B1 | FLAVONE CARBOXYLIC ACID DERIVATIVES | Shudo, Koichi, Prof. Dr. (JP) | 1991-10-02 | — | — | EP | claimed |