Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326258 | 0.87 | LMNA (0.36) | HSP90AA1HSP90AB1LMNAL3MBTL1NPC1 | |
| SCHEMBL10552817 | 0.86 | LMNA (0.38) | LMNAL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10550678 | 0.84 | LMNA (0.37) | HSP90AA1LMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL9324082 | 0.78 | HSP90AB1 (0.36) | HSP90AA1HSP90AB1LMNASMN1; SMN2MAPT | |
| SCHEMBL10563385 | 0.77 | NPC1 (0.38) | HSP90AA1LMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL9325338 | 0.74 | ATM (0.39) | HSP90AA1LMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9325343 | 0.73 | POLB (0.37) | HSP90AA1LMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL10361019 | 0.71 | HTR7 (0.37) | HSP90AA1LMNAL3MBTL1HTR7ADRA1D | |
| SCHEMBL2106591 | 0.70 | MAPK1 (0.53) | HSP90AA1HSP90AB1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL10554973 | 0.69 | LMNA (0.42) | LMNANPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4844731-A | HERBICIDES FOR RICE PADDYS | IDEMITSU COMPANY CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |