SCHEMBL9326258

SCHEMBL9326258

CSc1nc(N)nc(NC(C)CSc2cc(C)ccc2C)n1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
HSP90AA1 P07900 4/20 0.35
HSP90AB1 P08238 3/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 4/20 0.33
MAPT P10636 2/20 0.33
GAA P10253 1/20 0.33
MEN1 O00255 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
TERT O14746 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10550507 0.87 HSP90AA1 (0.44) LMNAL3MBTL1HSP90AA1HSP90AB1NPC1
SCHEMBL9325343 0.86 POLB (0.37) LMNAL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL9324082 0.82 HSP90AB1 (0.36) LMNAHSP90AA1HSP90AB1SMN1; SMN2MAPT
SCHEMBL10552305 0.80 KMT2A (0.37) LMNAL3MBTL1HSP90AA1HSP90AB1NPC1
SCHEMBL9325338 0.73 ATM (0.39) LMNAL3MBTL1HSP90AA1MAPTGAA
SCHEMBL10552817 0.73 LMNA (0.38) LMNAL3MBTL1NPC1RAB9AHTT
SCHEMBL10554973 0.73 LMNA (0.42) LMNANPC1RAB9ASMN1; SMN2MAPT
SCHEMBL10362067 0.72 HTR7 (0.39) L3MBTL1HSP90AA1HSP90AB1GAA
SCHEMBL10550678 0.71 LMNA (0.37) LMNAL3MBTL1HSP90AA1NPC1RAB9A
SCHEMBL9325367 0.71 KMT2A (0.36) LMNAL3MBTL1HSP90AA1HSP90AB1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273328-B1 Triazine derivatives and herbicides containing said derivatives IDEMITSU KOSAN CO (JP) 1994-03-09 EP disclosed
US-4844731-A HERBICIDES FOR RICE PADDYS IDEMITSU COMPANY CO., LTD. (JP) 1989-07-04 US disclosed
EP-0273328-A2 Triazine derivatives and herbicides containing said derivatives IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-07-06 EP disclosed