Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.77 |
| ▸ | RAB9A | P51151 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | HTT | P42858 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | PDE5A | O76074 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | PDE1A | P54750 | 1/20 | 0.57 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.57 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871628 | 0.87 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL15427054 | 0.84 | NPC1 (0.75) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL10548947 | 0.76 | LMNA (0.59) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL4726533 | 0.76 | RAB9A (0.64) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL9677782 | 0.75 | SMN1; SMN2 (0.71) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL91572 | 0.75 | RAB9A (0.66) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL3405939 | 0.74 | RAB9A (0.77) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL6796683 | 0.74 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| Acetic Acid SCHEMBL9385119 | 0.74 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2LMNAHTT | |
| SCHEMBL8402291 | 0.74 | MAPT (0.73) | NPC1RAB9ASMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826861-A | MEDICAL BACTERICIDES OR FUNGICIDES | ALBERT ROLAND, S.A. (FR) | 1989-05-02 | — | — | US | disclosed |